1484-34-0 Usage
Uses
Used in Pharmaceutical and Chemical Research:
(1-phenyl-1H-benzo[d]imidazol-2-yl)methanol is used as a building block for the synthesis of other complex molecules. Its unique structure allows it to be a valuable component in the development of new pharmaceuticals and chemical compounds.
Used in Therapeutic Applications:
(1-phenyl-1H-benzo[d]imidazol-2-yl)methanol has been studied for its potential therapeutic properties, including its ability to inhibit certain enzymes. This makes it a promising candidate for the treatment of various diseases, although further research is needed to fully understand its therapeutic potential.
Used as a Fluorescent Probe in Biological Research:
(1-phenyl-1H-benzo[d]imidazol-2-yl)methanol has been investigated for its use as a fluorescent probe. This application allows researchers to detect and quantify certain biological molecules, which can be crucial in understanding biological processes and developing new diagnostic tools.
Overall, (1-phenyl-1H-benzo[d]imidazol-2-yl)methanol has a range of potential uses in both research and industry due to its unique chemical structure and properties. Its versatility as a building block, therapeutic agent, and fluorescent probe highlights its importance in the fields of chemistry, biology, and medicine.
Check Digit Verification of cas no
The CAS Registry Mumber 1484-34-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,4,8 and 4 respectively; the second part has 2 digits, 3 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 1484-34:
(6*1)+(5*4)+(4*8)+(3*4)+(2*3)+(1*4)=80
80 % 10 = 0
So 1484-34-0 is a valid CAS Registry Number.
1484-34-0Relevant academic research and scientific papers
Sustainable Synthesis of 2-Hydroxymethylbenzimidazoles using D-Fructose as a C2 Synthon
Raja, Dineshkumar,Philips, Abigail,Sundaramurthy, Devikala,Chandru Senadi, Gopal
supporting information, p. 3754 - 3759 (2021/10/14)
D-fructose, a biomass-derived carbohydrate has been identified as an environmentally benign C2 synthon in the preparation of synthetically useful 2-hydroxymethylbenzimidazole derivatives by coupling with 1,2-phenylenediamines. Proof of concept was established by synthesizing 23 examples using BF3.OEt2 (20 mol%), TBHP (5.5 M, decane) (1.0 equiv.) in CH3CN at 90 °C for 1 h. The pivotal features of this method include metal-free conditions, short time, good functional group tolerance, gram scale feasibility and the synthesis of benzimidazole fused 1,4-oxazine. Control studies with conventional C2 synthons did not produce the desired product, thus suggesting a new reaction pathway from D-fructose.
FREE-RADICAL HYDROXYMETHYLATION OF BENZIMIDAZOLE
Khristich, B.I.,Tsupak, E.B.,Kononogova, O.I.
, p. 1299 - 1302 (2007/10/02)
Several benzimidazole derivatives were subjected to free-radical hydroxymethylation.Benzimidazole displays lower activity than quinoline in the first stage of the transformation, viz., in the addition of the hydroxymethyl radical.The yields of hydroxymeth
