1484-93-1Relevant articles and documents
Phenylation of pyrimidinones using diphenyliodonium salts
Jacobsen, Stig Andre,Rodbotten, Synne,Benneche, Tore
, p. 3265 - 3268 (1999)
Pyrimidinones 1 have been phenylated under basic conditions using diphenyliodonium salts, and the effect of substituents on the yield and regiochemistry has been studied. The Royal Society of Chemistry 1999.
COMPOUNDS AND METHODS FOR TREATING INFLAMMATORY AND FIBROTIC DISORDERS
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Page/Page column 81, (2009/12/28)
Disclosed are compounds and methods for treating inflammatory and fibrotic disorders, including methods of modulating a stress activated protein kinase (SAPK) system with an active compound, wherein the active compound exhibits low potency for inhibition of the p38 MAPK; and wherein the contacting is conducted at a SAPK-modulating concentration that is at a low percentage inhibitory concentration for inhibition of the p38 MAPK by the compound. Also disclosed are derivatives and analogs of pirfenidone, useful for modulating a stress activated protein kinase (SAPK) system.
Efficient N-arylation and N-alkenylation of the five DNA/RNA nucleobases
Jacobsen, Mikkel F.,Knudsen, Martin M.,Gothelf, Kurt V.
, p. 9183 - 9190 (2007/10/03)
(Chemical Equation Presented) A general approach to N-arylation and N-alkenylation of all five DNA/RNA nucleobases at the nitrogen atom normally attached to the sugar moiety in DNA or RNA has been developed. Various protected or masked nucleobases engaged
