148428-94-8Relevant articles and documents
Synthesis, antiviral activity and molecular modeling of oxoquinoline derivatives
Santos, Fernanda da C.,Abreu, Paula,Castro, Helena C.,Paixao, Izabel C.P.P.,Cirne-Santos, Claudio C.,Giongo, Viveca,Barbosa, Juliana E.,Simonetti, Bruno R.,Garrido, Valeria,Bou-Habib, Dumith Chequer,Silva, David de O.,Batalha, Pedro N.,Temerozo, Jairo R.,Souza, Thiago M.,Nogueira, Christiane M.,Cunha, Anna C.,Rodrigues, Carlos R.,Ferreira, Vitor F.,de Souza, Maria C.B.V.
scheme or table, p. 5476 - 5481 (2009/12/09)
In the present article, we describe the synthesis, anti-HIV1 profile and molecular modeling evaluation of 11 oxoquinoline derivatives. The structure-activity relationship analysis revealed some stereoelectronic properties such as LUMO energy, dipole momen
