148431-61-2Relevant academic research and scientific papers
Synthesis of a Trisaccharide Repeating Unit of the O-Antigen from Burkholderia multivorans and Its Oligomers
Zhang, Xin,Gu, Guofeng,Guo, Zhongwu
, p. 7075 - 7085 (2015/11/16)
Burkholderia multivorans is a Gram-negative bacterium, and an important opportunistic human pathogen that can cause fatal infections. Its O-antigens are useful templates for the development of carbohydrate-based vaccines. A highly convergent and efficient
β-Rhamnosides from 6-thio mannosides
Christina, Alphert E.,Es, Daan Van Der,Dinkelaar, Jasper,Overkleeft, Hermen S.,Marel, Gijsbert A. Van Der,Codee, Jeroen D. C.
supporting information; experimental part, p. 2686 - 2688 (2012/04/10)
Upon condensation of 6-thio-6-deoxy-mannosyl donors 1,2-cis products are obtained with a high degree of stereoselectivity. Subsequent reductive removal of the 6-thio functionality gives 1,2-cis rhamnosides. The 1,2-cis-selectivity can be rationalized with
Synthesis, conformational analysis, and the glycosidic coupling reaction of substituted 2,7-dioxabicyclo[4.1.0]heptanes: 1,2-anhydro-3,4-di-O-benzyl-β-L- and β-D-rhamnopyranoses
Chen,Kong,Cao
, p. 107 - 117 (2007/10/02)
1,2-Anhydro-3,4-di-O-benzyl-α-L-rhamnopyranose was synthesized from L-rhamnose, while the D-enantiomer was synthesized from methyl 6-deoxy-2,3-O-isopropylidene-α-D-mannopyranoside. For both of the syntheses, the key intermediates were 2-O-acetyl-3,4-di-O-
