148485-16-9Relevant academic research and scientific papers
Synthetic models for the glucose tolerance factor: The spectroscopic characterization and toxicity studies of monomeric and dimeric Cr(III) species
Galuszka, Gabriela,Cieslak-Golonka, Maria,Szelag, Adam,Starosta, Jan,Wojciechowska, Agnieszka
, p. 3785 - 3794 (1998)
A number of chromium(III) complexes with glycine, cysteine, glutamic and nicotinic acids-models for biologically active Cr(III) species have been prepared and characterized with physicochemical methods (UVVis, IR spectra, magnetic moments). Four of them have been also tested for their toxicity. On the basis of CF calculation it was found that only the nicotinates were octahedral Cr(III) species. Other complexes exhibited a tetragonal deformations. Based upon 10 Dq values, the sequence of the ligand field strength was found to be: glycine>cysteine≈glutamic acid>nicotinic acid. The likely structures were proposed for the isolated compounds. The preliminary toxicity studies showed that all tested complexes appeared to be non-toxic and can be potentially applied as chromium nutrition products.
