148530-36-3

Upstream product

• 82586-61-6 ethyl 2-bromo-4-phenylbutanoate 
• 148530-35-2 (R)-Ethyl 3-Amino-4-oxo-2,3,4,5-tetrahydropyrrolo<2,1-b><1,3,4>thiadiazepine-5-acetate 
• 88767-98-0 ethyl (R)-4-phenyl-2-<<(trifluoromethyl)sulfonyl>oxy>butyrate 
• 149543-60-2 (R)-Ethyl 3-<(Benzyloxycarbonyl)amino>-4-oxo-2,3,4,5-tetrahydropyrrolo<2,1-b><1,3,4>thiadiazepine-5-acetate 
• 149543-62-4 (R)-2-<(Benzyloxycarbonyl)amino>-3-iodo-N-(2-thiocyanato-1-pyrrolyl)propanamide 
• 149543-54-4 (R)-3-<(Benzyloxycarbonyl)amino>-2,3,4,5-tetrahydropyrrolo<2,1-b><1,3,4>thiadiazepin-4-one 
• 149543-61-3 (R)-2-<(Benzyloxycarbonyl)amino>-3-iodo-N-(1-pyrrolyl)propanamide 
• 149543-56-6 (R)-2-<(Benzyloxycarbonyl)amino>-3-chloro-N-(1-pyrrolyl)propanamide 
• 149543-55-5 (S)-2-<(Benzyloxycarbonyl)amino>-3-hydroxy-N-(1-pyrrolyl)propanamide 

Downstream Products

• 148530-34-1 (3R,1'S)-3-<(1-Carboxy-3-phenylpropyl)amino>-4-oxo-2,3,4,5-tetrahydropyrrolo<2,1-b><1,3,4>thiadiazepine-5-acetic acid 
• 148530-33-0 (3R,1'R)-3-<(1-Carboxy-3-phenylpropyl)amino>-4-oxo-2,3,4,5-tetrahydropyrrolo<2,1-b><1,3,4>thiadiazepine-5-acetic acid 

Relevant academic research and scientific papers

Asymmetric synthesis of pyrrolo[2,1-b][1,3,4]thiadiazepine derivatives

The asymmetric synthesis of compound 2, with potential ACE inhibitory activity, is reported. The key intermediate 3 contains the novel heterocyclic nucleus pyrrolo[2,1-b][1,3,4]thiadiazepine. This compound has been prepared through a sequence involving py