148583-64-6Relevant articles and documents
Antipsychotic substituted piperidine derivatives
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, (2008/06/13)
The present invention relates to certain novel substituted piperidine derivatives of formula (I) to processes for their preparation, to pharmaceutical formulations containing them and to their use in medical therapy, particularly in the treatment of psych
Hindered rotation congeners of mazapertine: High affinity ligands for the 5-HT(1A) receptor
Baxter, Ellen W.,Reitz, Allen B.
, p. 763 - 768 (2007/10/03)
Hindered rotation analogs of the antipsychotic mazapertine (1) were prepared. These compounds exhibited high affinity for the 5-HT(1A) receptor, but not for other serotonin or dopamine receptors. The related β-carboline structures were also synthesized an
A New Arylpiperazine Antipsycholic with High D2/D3/5-HT1A/α1A-Adrenergic Affinity and a Low Potential for Extrapyramidal Effects
Reitz, Allen B.,Bennett, Debra J.,Blum, Paul S.,Codd, Ellen E.,Maryanoff, Cynthia A.,at al.
, p. 1060 - 1062 (2007/10/02)
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