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148638-76-0

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148638-76-0 Usage

General Description

(S)-tert-Butyl 2-((tosyloxy)Methyl)Morpholine-4-carboxylate is a chemical compound that belongs to the class of morpholine derivatives. It is a tosylate ester, which means it contains a tosylate group (tosyloxy) attached to the molecule. (S)-tert-Butyl 2-((tosyloxy)Methyl)Morpholine-4-carboxylate is used in organic synthesis and pharmaceutical research as a potential precursor or intermediate for the synthesis of various bioactive compounds or pharmaceutical agents. The tert-butyl group in the molecule provides stability and sterically hinders certain reactions, making it a useful building block in organic chemistry. The tosylate group can also participate in various substitution reactions, making this compound versatile and valuable in synthetic chemistry.

Check Digit Verification of cas no

The CAS Registry Mumber 148638-76-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,8,6,3 and 8 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 148638-76:
(8*1)+(7*4)+(6*8)+(5*6)+(4*3)+(3*8)+(2*7)+(1*6)=170
170 % 10 = 0
So 148638-76-0 is a valid CAS Registry Number.

148638-76-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name (S)-4-tert-butoxycarbonyl-2-p-toluenesulfonyloxymethylmorpholine

1.2 Other means of identification

Product number -
Other names (S)-tert-butyl 2-((tosyloxy)methyl)morpholine-4-carboxylate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:148638-76-0 SDS

148638-76-0Relevant articles and documents

COMPOUNDS USEFUL FOR INHIBITING CDK7

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Page/Page column 48, (2021/12/08)

CDK7 inhibitors according to the formula (I): wherein X is -CH(OH)CH3, -CHFCH3, -CF2CH3, or -CF3; Y is -CH=CH2 or C2H=C2H2; and Z is CH(CH3)

Solid dispersions containing an apoptosis-inducing agent

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Page/Page column 182-183, (2019/03/15)

A pro-apoptotic solid dispersion comprises, in essentially non-crystalline form, a Bcl-2 family protein inhibitory compound of Formula I as defined herein, dispersed in a solid matrix that comprises (a) a pharmaceutically acceptable water-soluble polymeric carrier and (b) a pharmaceutically acceptable surfactant. A process for preparing such a solid dispersion comprises dissolving the compound, the polymeric carrier and the surfactant in a suitable solvent, and removing the solvent to provide a solid matrix comprising the polymeric carrier and the surfactant and having the compound dispersed in essentially non-crystalline form therein. The solid dispersion is suitable for oral administration to a subject in need thereof for treatment of a disease characterized by overexpression of one or more anti-apoptotic Bcl-2 family proteins, for example cancer.

Novel Triazolopyrazine Derivatives and Use Thereof

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Paragraph 0119; 0126, (2017/07/31)

The present invention relates to novel triazolopyrazine derivatives or a pharmaceutically acceptable salt, and a pharmaceutical composition for inhibiting c-Met tyrosine kinase activity and a pharmaceutical composition for preventing or treating hyperproliferative disorders, containing the same as active ingredients. The present invention effectively inhibits c-Met tyrosine kinase activity, thereby being able to be useful as a drug for various hyperproliferative disorders such as cancers, psoriasis, rheumatoid arthritis, diabetic retinitis, etc. related to excessive cell proliferation and growth by abnormal kinase activation.

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