148651-39-2 Usage
Uses
Used in Organic Synthesis:
4-Bromophenylzinc iodide is used as a reagent for introducing the 4-bromophenyl group into organic molecules, allowing for the synthesis of a wide range of compounds with potential applications in various industries.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 4-bromophenylzinc iodide is used as a key intermediate in the synthesis of various pharmaceutical compounds, contributing to the development of new drugs with improved therapeutic properties.
Used in Material Science:
4-Bromophenylzinc iodide is employed in the synthesis of advanced materials, such as polymers and organic semiconductors, which have potential applications in electronic devices, sensors, and energy storage systems.
Used in Cross-Coupling Reactions:
In the field of organic chemistry, 4-bromophenylzinc iodide is used as a reactant in cross-coupling reactions, such as the Negishi coupling, to form carbon-carbon bonds between an organic halide and an organozinc reagent. This process is crucial for the construction of complex organic molecules and the development of novel chemical compounds with specific properties and applications.
Check Digit Verification of cas no
The CAS Registry Mumber 148651-39-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,8,6,5 and 1 respectively; the second part has 2 digits, 3 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 148651-39:
(8*1)+(7*4)+(6*8)+(5*6)+(4*5)+(3*1)+(2*3)+(1*9)=152
152 % 10 = 2
So 148651-39-2 is a valid CAS Registry Number.
InChI:InChI=1/C6H4Br.HI.Zn/c7-6-4-2-1-3-5-6;;/h2-5H;1H;/q;;+1/p-1/rC6H4BrIZn/c7-5-1-3-6(9-8)4-2-5/h1-4H
148651-39-2Relevant academic research and scientific papers
Enantioselective Conjugate Addition of Stabilized Arylzinc Iodide to Enones: an Improved Protocol of the Hayashi Reaction
Casotti, Gianluca,Rositano, Vincenzo,Iuliano, Anna
, p. 1126 - 1131 (2020/12/17)
Stabilised arylzinc iodide, prepared by direct insertion of zinc into aryl iodides, were used as nucleophiles in the Hayashi Rh-catalysed enantioselective conjugate addition to enones. The reaction conditions were optimized in the addition of phenylzinc i
Ni-Catalyzed Regioselective Dicarbofunctionalization of Unactivated Olefins by Tandem Cyclization/Cross-Coupling and Application to the Concise Synthesis of Lignan Natural Products
Kc, Shekhar,Basnet, Prakash,Thapa, Surendra,Shrestha, Bijay,Giri, Ramesh
, p. 2920 - 2936 (2018/03/09)
We disclose a (terpy)NiBr2-catalyzed reaction protocol that regioselectively difunctionalizes unactivated olefins with tethered alkyl halides and arylzinc reagents. The reaction shows an excellent functional group tolerance (such as ketones, es
Ultrasound-Promoted Synthesis of Arylzinc Compounds Using Zinc Powder and Their Application to Palladium(0)-Catalyzed Synthesis of Multifunctional Biaryls
Takagi, Kentaro
, p. 469 - 472 (2007/10/02)
Arylzinc compounds containing electron-withdrawing groups such as CO2CH3, CON(CH3)2, CN, Br, Cl, or CF3 at ortho position were prepared readily by the ultrasound-promoted reaction of aryl iodides with zinc powder, which were applied to palladium(0)-catalyzed cross-coupling with aryl halides to afford unsymmetrical and multifunctional biaryls in good yields.
