4-BROMOPHENYLZINC IODIDE

Base Information

• Chemical Name: 4-BROMOPHENYLZINC IODIDE
• CAS No.: 148651-39-2
• Molecular Formula: C6H4 Br I Zn
• Molecular Weight: 348.296
• Mol file: 148651-39-2.mol

Synonyms:4-Bromophenylzinciodide

Chemical Property of 4-BROMOPHENYLZINC IODIDE

Chemical Property:

• Refractive Index: ">
• Boiling Point: °Cat760mmHg
• Flash Point: °C
• PSA: 0.00000
• Density: g/cm³
• LogP: 3.13250
• Storage Temp.: 2-8°C
• Sensitive.: Air Sensitive

Purity/Quality:

99% ^*data from raw suppliers

4-Bromophenylzinc iodide solution 0.5M in THF ^*data from reagent suppliers

Safty Information:

• Hazard Codes: F,Xn
• Statements: 11-14-19-22-36/37/38-40-36/37
• Safety Statements: 16-26-33-36-36/37

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-BROMOPHENYLZINC IODIDE

There total 1 articles about 4-BROMOPHENYLZINC IODIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

1,4-bromoiodobenzene (589-87-7) + zinc (7440-66-6) → (4-bromophenyl)zinc iodide (148651-39-2)

Guidance literature:

With water; In further solvent(s); byproducts: C6H5Br; Sonication; (N2); solvent = 1,1,3,3-tetramethylurea contg. water; 2 equivs. of Zn powder used; 50 °C; ultrasound applied for 20 h; 100% conversion; not isolated; conversion and yield detd. by quenching with I2;

DOI:10.1246/cl.1993.469

Reference yield: 98.0%

carbon dioxide (124-38-9,18923-20-1) + (4-bromophenyl)zinc iodide (148651-39-2) → 4-Bromobenzoic acid (586-76-5)

Guidance literature:

carbon dioxide; (4-bromophenyl)zinc iodide; With lithium chloride; In N,N-dimethyl-formamide; at 50 ℃; for 48h; under 760.051 Torr;

With hydrogenchloride; water; In N,N-dimethyl-formamide;

DOI:10.1021/ol900528h

Reference yield: 91.0%

cyclohexenone (930-68-7) + (4-bromophenyl)zinc iodide (148651-39-2) → (R)-3-(4-bromophenyl)cyclohexan-1-one

Guidance literature:

With chlorobis(ethylene)rhodium(I) dimer; N,N,N,N,-tetramethylethylenediamine; (R)-2,2'-bis(diphenylphosphanyl)-1,1'-binaphthyl; In 1,2-dimethoxyethane; at 20 ℃; for 28h; enantioselective reaction; Inert atmosphere;

DOI:10.1002/adsc.202001141

upstream raw materials:

1,4-bromoiodobenzene

zinc

Downstream raw materials:

(4-bromophenyl)(4-nitrophenyl)methan-1-ol

4-bromophenyl(4-nitrophenyl)methanone

1,4-bromoiodobenzene

4-(4-bromophenyl)bromobenzene

Refernces

• 1、 Kc, Shekhar,Basnet, Prakash,Thapa, Surendra,Shrestha, Bijay,Giri, Ramesh. "Ni-Catalyzed Regioselective Dicarbofunctionalization of Unactivated Olefins by Tandem Cyclization/Cross-Coupling and Application to the Concise Synthesis of Lignan Natural Products". . p. 2920 - 2936. Retrieved 2018/03/09.