148679-67-8

Basic information

• Product Name: 6,7-dimethoxy-1-(3,4-dimethoxybenzyl)-N-methoxycarbonyl-1,2,3,4-tetrahydroisoquinoline
• Synonyms: 6,7-dimethoxy-1-(3,4-dimethoxybenzyl)-N-methoxycarbonyl-1,2,3,4-tetrahydroisoquinoline
• CAS NO: 148679-67-8
• Molecular Weight: 401.459
• Mol File: 148679-67-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 6,7-dimethoxy-1-(3,4-dimethoxybenzyl)-N-methoxycarbonyl-1,2,3,4-tetrahydroisoquinoline(CAS DataBase Reference)
• NIST Chemistry Reference: 6,7-dimethoxy-1-(3,4-dimethoxybenzyl)-N-methoxycarbonyl-1,2,3,4-tetrahydroisoquinoline(148679-67-8)
• EPA Substance Registry System: 6,7-dimethoxy-1-(3,4-dimethoxybenzyl)-N-methoxycarbonyl-1,2,3,4-tetrahydroisoquinoline(148679-67-8)

Safety Data

• Hazardous Substances Data: 148679-67-8(Hazardous Substances Data)

Upstream product

• 68-12-2 N,N-dimethyl-formamide 
• 164228-31-3 1-(2-bromo-3,4-dimethoxybenzyl)-7-hydroxy-6-methoxy-N-methoxycarbonyl-1,2,3,4-tetrahydroisoquinoline 
• 4927-55-3 1,2-bis(3,4-dimethoxyphenyl)ethanone 
• 148679-66-7 (2-Benzenesulfinyl-ethyl)-[1,2-bis-(3,4-dimethoxy-phenyl)-ethyl]-carbamic acid methyl ester 
• 148679-64-5 [1,2-Bis-(3,4-dimethoxy-phenyl)-ethyl]-(2-phenylsulfanyl-ethyl)-amine 

Downstream Products

• 1699-51-0 laudanosine 

Relevant articles and documents

Synthesis of the salutaridine and aporphine skeleton via palladium(0) catalyzed cyclization and S(RN)1 reaction of 2'-bromoreticulines

The intramolecular aryl-aryl-coupling reactions of 2'-bromoreticulines are described. Their regioselectivity depends on the cyclization method. The palladium(0) catalyzed reaction of 22 leads preferentially to the salutaridine derivative 27, whilst via the photochemically induced S(RN)1 reaction of 22 the aporphine skeleton 24 is obtained.