4927-55-3

Basic information

• Product Name: 1-[2-(1,3-benzothiazol-2-yl)-2-cyanoethenyl]-3-prop-2-en-1-ylthiourea
• CAS NO: 4927-55-3
• Molecular Formula: C₁₈H₂₀O₅
• Molecular Weight: 300.4019
• Mol File: 4927-55-3.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 437.4°C at 760 mmHg
• Flash Point: 218.3°C
• Density: 1.319g/cm³
• Vapor Pressure: 7.49E-08mmHg at 25°C
• Refractive Index: 1.697
• CAS DataBase Reference: 1-[2-(1,3-benzothiazol-2-yl)-2-cyanoethenyl]-3-prop-2-en-1-ylthiourea(CAS DataBase Reference)
• NIST Chemistry Reference: 1-[2-(1,3-benzothiazol-2-yl)-2-cyanoethenyl]-3-prop-2-en-1-ylthiourea(4927-55-3)
• EPA Substance Registry System: 1-[2-(1,3-benzothiazol-2-yl)-2-cyanoethenyl]-3-prop-2-en-1-ylthiourea(4927-55-3)

Safety Data

• Hazardous Substances Data: 4927-55-3(Hazardous Substances Data)

Usage

Chemical structure

A thiourea derivative containing a benzothiazole moiety and a cyanoethenyl group.

Pharmaceuticals

Due to its unique structure and properties, it may possess interesting pharmacological properties.

Materials science

The cyanoethenyl group may be utilized for further chemical modifications and the development of new materials.

Biological activities

As a thiourea derivative, it is known for its diverse biological activities.

Versatility

The cyanoethenyl group serves as a versatile functional group for further chemical modifications in organic synthesis and material science.

Exploration

The compound has the potential to be further explored for its various applications in different fields of science and industry.

Upstream product

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Downstream Products

• 76306-70-2 N-<1,2-bis(3,4-dimethoxyphenyl)ethyl>formamide 
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• 120801-96-9 4,5-Bis-(3,4-dimethoxy-phenyl)-2,6-diphenyl-pyrimidine 
• 120801-97-0 1,2,3-Tris-(3,4-dimethoxy-phenyl)-6,7-dimethoxy-naphthalene 
• 35989-93-6 6,7-dimethoxy-1-methyl-3-(3,4-dimethoxyphenyl)isoquinoline 
• 120801-93-6 C₁₈H₁₉ClO₄ 
• 82552-22-5 3-(3,4-Dimethoxy-phenyl)-1-ethyl-6,7-dimethoxy-isoquinoline 
• 120801-95-8 4,5-Bis-(3,4-dimethoxy-phenyl)-2,6-diethyl-pyrimidine 
• 152587-68-3 Acetic acid {[1,2-bis-(3,4-dimethoxy-phenyl)-ethyl]-formyl-amino}-methyl ester 
• 24126-93-0 6,7-dimethoxy-3-(3,4-dimethoxyphenyl)-4H-chromen-4-one 
• 2150-38-1 methyl 3,4-dimethoxybenzoate 

Relevant articles and documents

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Facile method for the large-scale synthesis of 6,7,4′-trihydroxyisoflavanone

6,7,4′-Trihydroxyisoflavanone, the main source of which is extracted from soybeans, has been found to have diverse significant bioactivities. A large-scale, cost-effective, and facile chemical synthesis of 6,7,4′-trihydroxyisoflavanone is presented herein. Its synthesis is characterized by three steps with an overall yield of 71% and a purity or more than 99.0%. This reaction can be scaled up to multikilogram quantities, providing a solid basis for its further bioactivity studies and drug development. With this same method, 6,7,3′,4′-tetrahydroxyisoflavanone, an analog of 6,7,4′-trihydroxyisoflavanone, also can be largely prepared, indicating this modified synthetic method is potentially available for large-scale synthesis of a broad range of multihydroxyl isoflavanones.

Towards a facile synthesis of triarylethanones: Palladium-catalyzed arylation of ketone enolates under homogeneous and heterogeneous conditions

The palladium-catalyzed regioselective α-monoarylation of deoxybenzoins and α,α-diarylation of acetophenones provides general, efficient access to 1,2,2-triarylethanones. After a comprehensive search for suitable experimental conditions to optimize such transformations, both reactions are alternatively conducted by means of either commercially available polymer-anchored catalysts or a very simple homogeneous catalytic system, thus avoiding the use of complex ligands. In addition, the synthesis of deoxybenzoins employing polymer-supported fibrous palladium catalysts is reported for the first time, and the excellent catalyst recycling properties suggest applicability to industrial purposes.