14869-40-0

Basic information

• Product Name: α-ethoxy-p-methylacetophenone
• Synonyms: α-ethoxy-p-methylacetophenone
• CAS NO: 14869-40-0
• Molecular Weight: 178.231
• Mol File: 14869-40-0.mol

Chemical Properties

• CAS DataBase Reference: α-ethoxy-p-methylacetophenone(CAS DataBase Reference)
• NIST Chemistry Reference: α-ethoxy-p-methylacetophenone(14869-40-0)
• EPA Substance Registry System: α-ethoxy-p-methylacetophenone(14869-40-0)

Safety Data

• Hazardous Substances Data: 14869-40-0(Hazardous Substances Data)

Upstream product

• 556-64-9 methyl thiocyanate 
• 17263-64-8 2-diazo-1-(4-methylphenyl)ethanone 
• 14077-58-8 ethoxyacetyl chloride 
• 64-17-5 ethanol 
• 122-00-9 para-methylacetophenone 

Relevant articles and documents

Direct Synthesis of α-Alkoxy Ketones by Oxidative C–O Bond Formation

A convenient method to prepare α-alkoxy ketones has been developed by oxidative coupling of aryl methyl ketones and alcohols. With aqueous tert-butyl hydroperoxide (6.0 equiv.) as the oxidant, tetrabutylammonium iodide (20 mol-%) as the catalyst, and TsNHNH2(1.0 equiv.) as the additive, ketones underwent direct alkoxylation to give α-methoxy or α-ethoxy ketones in moderate to good yields.

ACID-CATALYZED DECOMPOSITION OF DIAZO CARBONYL COMPOUNDS. II. SYNTHESIS OF 2- OR 5-HETEROATOM-SUBSTITUTED OXAZOLES.

The BF//3-catalyzed decomposition of m- and p-substituted alpha -diazoacetophenones in excess of methyl thiocyanate and ethyl thiocyanate gave the corresponding 2-methylthio-, and 2-ethylthio-5-aryloxazoles, respectively in good yields along with s-alkyl-