148727-46-2

Upstream product

• 160695-09-0 (S)-3-(4-Methoxy-phenyl)-3a-methyl-4,5,6,7-tetrahydro-3aH-indene 
• 126971-21-9 (9S)-9-Methyl-1-phenylbicyclo<4.3.0>nona-1(2),3(4)-diene 
• 101758-35-4 (S)-(-)-4-methyl-2-cyclohexen-1-one 

Downstream Products

• 160695-13-6 (3aS,6aS)-6a-(4-methoxyphenoxymethyl)-5',5'-dimethyl-3a,6a-dihydrospiro<4H-cyclopentafuran-4,2'-<1,3>dioxan>-2(3H)-one 
• 160695-15-8 (3aS,6aS)-3-<(Z)-allylidene>-6a-(4-methoxyphenoxymethyl)-5',5'-dimethyl-3a,6a-dihydrospiro<4H-cyclopentafuran-4,2'-<1,3>dioxan>-2(3H)-one 
• 160796-86-1 (3aS,6aS)-3-<(E)-allylidene>-6a-(4-methoxyphenoxymethyl)-5',5'-dimethyl-3a,6a-dihydrospiro<4H-cyclopentafuran-4,2'-<1,3>dioxan>-2(3H)-one 
• 1027543-32-3 C₂₄H₃₀O₉S 
• 160695-14-7 (3R,3aS,6aS)-6a-(4-methoxyphenoxymethyl)-5',5'-dimethyl-3-<(1R)-1-hydroxyallyl>-3a,6a-dihydrospiro<4H-cyclopentafuran-4,2'-<1,3>dioxan>-2(3H)-one 
• 160695-20-5 (4S,5S)-5-<1-(hydroxymethyl)-(E)-buta-1,3-dienyl>-4-(4-methoxyphenoxymethyl)-5',5'-dimethylspirodioxan>-4-ol 

Relevant academic research and scientific papers

Kinetic resolution in Diels-Alder processes

Examples of highly efficient kinetic resolutions with the bicylic chiral cyclopentadiene 1 and several selected cyclic dienophiles are reported. In combination with a thermal retro-Diels-Alder process this procedure provides easy access to both enantiomer

Enantiopure Didemnenones via Kinetic Resolution

Kinetic resolution in an enantioselective Diels-Alder process provided the starting material for an imporved and simplified approach to all the didemnenones via the lactone 16.