1488-34-2

Upstream product

• 36282-40-3 (3-methoxyphenyl)magnesium bromide 
• 141-78-6 ethyl acetate 
• 39193-85-6 3,3'-dimethoxybenzophenone 
• 1779-49-3 Methyltriphenylphosphonium bromide 
• 19493-09-5 Methylenetriphenylphosphorane 
• 574738-22-0 1,1-bis-(3-methoxy-phenyl)-ethanol 

Downstream Products

• 80554-92-3 3-Methoxy-5-(3-methoxy-phenyl)-8-aza-benzo[a]anthracene-7,12-dione 
• 93404-03-6 3-methoxy-5-(m-methoxyphenyl)benzanthracene-7,12-dione 
• 54655-89-9 1,1,4,4-tetrakis(4-methoxyphenyl)butadiene 
• 574738-24-2 1,1,3-tris-(3-methoxyphenyl)-3-methyl-5-methoxyindane 
• 36707-27-4 1,2-bis(3-methoxyphenyl)ethane 
• 59647-77-7 bis(3-methoxyphenyl)acetylene 
• 39193-85-6 3,3'-dimethoxybenzophenone 
• 86927-83-5 3-Methoxy-5-(3-methoxy-phenyl)-11-aza-benzo[a]anthracene-7,12-dione 
• 93404-15-0 3-methoxy-5-(m-methoxyphenyl)naphtho<1,2-g>quinoxaline-7,12-dione 
• 59647-76-6 3,3'-(2-bromoethene-1,1-diyl)bis(methoxybenzene) 

Relevant academic research and scientific papers

Conformationally constrained compounds as dendrimer cores

There are provided novel chemical compounds and their uses in the preparation of polymers and oligomers, and the preparation of such compounds. In certain embodiments there are provided dendritic polymers and oligomers, of a type having at least four poly

Substituted 6,11-ethano-6,11-dihydrobenzo[b] quinolizinium salts and compositions and methods of use thereof

Substituted 6,11-ethano-6,11-dihydrobenzo[b]quinolizinium salts, pharmaceutical compositions containing them, and methods for the treatment of neurodegenerative disorders or neurotoxic injuries utilizing them, wherein the substituted 6,11-ethano-6,11-dihydrobenzo[b]quinolizinium salts have the formula: STR1 wherein: R1, R2, R3, R4, R5, R6, R7, X and p are as defined in the specification.

Discovery of 6,11-ethano-12,12-diaryl-6,11-dihydrobenzo[b]quinolizinium cations, a novel class of N-methyl-D-aspartate antagonists

6,11-Ethano-12,12-diaryl-6,11-dihydrobenzo[b]quinolizinium cations 8, a novel class of N-methyl-D-aspartate (NMDA) antagonists acting at the phencyclidine site, have been identified. Structure-activity relationship studies around the lead compound 8a led

Substituent-Dependent Electron-Transfer Induced Photooxygenation of 1,1-Diarylethylenes

Rates and products of 9,10-dicyanoanthracene-sensitized photooxygenations of 1,1-diarylethylenes (1a-r) in acetonitrile were studied.If at least one of the aryl groups carries an electron-donating substituent at the para (or ortho) position (1a-l), 3,3,6,6-tetraaryl-1,2-dioxanes (2a-l) are generated in high yields (85-100percent).Benzophenones (3) are the only other observable products. 1,1-Diphenylethylene (1n) and its m-methoxy (1m), p-chloro (1o,p), and p-nitro (1q,r) derivatives, however, yield mainly benzophenones (3m-r) (>50percent) (the p-nitro compounds only in the presence of biphenyl). 1,2-Dioxanes (2m-p), cyclobutanes (4n-p), and α-tetralones (5m-o) are obtained as side products.Dioxanes, benzophenones, and α-tetralones are products of electron-transfer induced oxygenations involving triplet ground-state molecular oxygen, 3O2.Singlet molecular oxygen, O2(1Δg), contributes to the benzophenone formation from strongly electron-donor substituted diarylethylenes.An exception is the most powerful electron-donor substituted diarylethylene 1a, with which O2(1Δg) undergoes an electron-transfer reaction affording dioxane 2a.Dioxane formation proceeds via free-radical cations 1.+, which enter into a chain reaction with 1, 3O2, and another molecule of 1 to yield dioxane 2 and a new radical cation 1.+ that maintains the chain reaction.The efficiency of this chain process, however, is found to be several orders of magnitude smaller than expected.To explain this result, a 1,6-biradical .1-1-O2. is proposed to be generated in this chain reaction as the product-determining intermediate that predominantly fragments into 3O2 and two molecules of 1.Cyclization to dioxane 2 and transformation to benzophenone 3 occur at presumably less than 0.1percent from this biradical.The pathways leading to cyclobutanes (4) and α-tetralones (5) are also discussed.