148906-73-4Relevant academic research and scientific papers
Facile preparation of methyl 5-aryl-4-hydroxyhex-2(E)-enoate, chiral synthon of bisabolane-type sesquiterpenes, based on lipase-catalyzed kinetic resolution and rearrangement of an aryl group
Fujii, Mikio,Yasuhara, Sumie,Akita, Hiroyuki
experimental part, p. 1286 - 1294 (2009/10/17)
The lipase-catalyzed enantioselective acetylation of racemic methyl (4S*,5S*)-4-aryl-5-hydroxyhex-2(E)-enoates 1a-h was performed and efficient resolutions were achieved (E >400) by using CAL-B. After brosylation of the obtained opti
