14893-83-5

Usage

Uses

Used in Pharmaceutical Industry:
(1E)-5-methyl-3-oxo-1-(phenylmethylidene)pyrazolidin-1-ium is used as a potential candidate in drug development for its structural features and biological activities, which may contribute to the creation of new therapeutic agents.
Used in Medicinal Chemistry Research:
(1E)-5-methyl-3-oxo-1-(phenylmethylidene)pyrazolidin-1-ium serves as a subject of study in medicinal chemistry to explore its interactions with biological targets and its potential to be modified for specific therapeutic applications.
Used in Agrochemical Development:
(1E)-5-methyl-3-oxo-1-(phenylmethylidene)pyrazolidin-1-ium may be utilized in the development of agrochemicals, given its potential biological activities that could be harnessed for applications in agriculture.
Used in Materials Science:
(1E)-5-methyl-3-oxo-1-(phenylmethylidene)pyrazolidin-1-ium could also be explored for uses in materials science, where its unique structural and chemical properties might be applied to develop new materials with specific functions or properties.
Further research is necessary to fully understand and realize the potential uses of (1E)-5-methyl-3-oxo-1-(phenylmethylidene)pyrazolidin-1-ium in these and other fields.

Upstream product

• 10234-76-1 5-methyl-pyrazolidin-3-one 
• 100-52-7 benzaldehyde 
• 623-43-8 methyl crotonate 
• 10544-63-5 ethyl crotonate 

Downstream Products

• 1070656-97-1 3-(3-n-butyl-5-phenyl-1H-pyrazol-1-yl)butanoic acid 
• 1070656-96-0 3-(3,5-diphenyl-1H-pyrazol-1-yl)butanoic acid 
• 1070656-94-8 7-n-butyl-3-methyl-5-phenyl-6-(p-toluenesulfonyl)-2,3-dihydro-5H-pyrazolo[1,2-a]pyrazol-1-one 
• 1070656-95-9 7-butylidene-3-methyl-5-phenyl-6-(p-toluenesulfonyl)-tetrahydro-pyrazolo[1,2-a]pyrazol-1-one 
• 1070657-08-7 C₂₆H₂₄N₂O₃S 
• 1260540-66-6 ethyl 7-methyl-5-oxo-1-phenyl-6,7-dihydro-1H,5H-pyrazolo[1,2-a]pyrazole-2-carboxylate 

Relevant academic research and scientific papers

Reactions of 3-methyl-2-oxopyrazolidinium ylides with phenylsulfonylacrylonitriles

A series of methyl oxopyrazolidinium ylides was reacted with (E)-3-(2-hydroxyphenyl)-2-(phenylsulfonyl)acrylonitrile and 2-phenylsulfonyl acrylonitrile to give rise to (1R,2S,3S)-5-methyl-7-oxo-1,3-p-substituteddiphenyl-2-(phenylsulfonyl)-hexahydropyrazolo[1,2-a]pyrazole-2-carbonitriles through a sequential reaction accompanying methyl pyrazolone and o-quinone methide releases possibly instead of an anticipated cycloaddition process and 1,3-dipolar cycloaddition route. All the new products were identified by means of spectral/physical characteristics including X-ray diffraction data and HRMS measurements. In addition, a plausible mechanism is proposed for hydroxyphenyl substituted acrylonitrile case.

Visible-Light-Mediated α-Amino Alkylation of Azomethine Imines: An Approach to N-(β-Aminoalkyl)pyrazolidinones

Herein, a mild and robust photocatalytic protocol for the combination of amino and pyrazolidinone functionalities through a radical α-amino alkylation of azomethine iminium ions is demonstrated. This method presents a high functional group tolerance provi

[3 + 2]-Cycloadditions of Azomethine Imines and Ynolates

A novel [3 + 2]-cycloaddition between azomethine imines and lithium ynolates is described to synthesize bicyclic pyrazolidinones. These bicyclic pyrazolidinones are versatile intermediates to form β-amino acids and monocyclic pyrazolidinones. High diaster

Microwave-assisted regioselective [1,3]-dipolar cycloaddition of 3-methyl-2-(substitutedbenzylidene)-5-oxopyrazolidin-2-ium-1-ides to benzothiophene 1,1-dioxide

A series of pyrazolidinium ylides was reacted with benzothiophene 1,1-dioxide to afford (3R,5S,5aS,10bS)-3-methyl-5-substitutedphenyl-2,3,5,5a-tetrahydrobenzo[4,5]thieno[3,2-c]pyrazolo[1,2-a]pyrazol-1(10bH )-one 6,6-dioxides under microwave irradiation an

Copper(I) acetate-catalyzed cycloaddition between azomethine imines and propiolates under additive-free conditions

Because propiolates easily undergo base-catalyzed self-Michael addition, most popular catalytic systems in CuAAC cannot be used in the cycloaddition between azomethine imines and propiolates, because such reactions usually require the use of tertiary amin

Copper(I) zeolites as heterogeneous and ligand-free catalysts: [3+2] cycloaddition of azomethine imines

Copper(I)-exchanged zeolites were used as heterogeneous ligand-free catalysts for [3+2] cycloaddition of azomethine ylides, which allows versatile, efficient, and highly regioselective synthesis of pyrazolone derivatives. These cheap and easy-to-prepare c

Palladium-catalyzed [3 + 3] cycloaddition of trimethylenemethane with azomethine imines

A palladium-catalyzed [3 + 3] cycloaddition of trimethylenemethane (TMM) with azomethine imines has been developed to produce hexahydropyridazine derivatives under simple and mild conditions. The use of substituted TMM precursors highlights the difference

PREPARATION OF CYCLIC α-HYDRAZINO ACIDS THROUGH N-ACYLHYDRAZONIUM INTERMEDIATES

An efficient synthesis of bicyclic hydrazine derivatives (5a) and (5b) through the intermediacy of exocyclic hydrazonium ions (4a) and (4b) is described.

BENZYLATION OF 1-BENZYLIDENE-3-PYRAZOLIDINIUM OXIDES

The benzylation of 1-benzylidene-5-phenyl-3-pyrazolidinium oxide (2a) gives five products including the "head to head" dimer of 2 (7) and the ring-opened 1-benzyl-1-cinnamoylhydrazone (4a).Similar behavior was also observed with ylides bearing various sub