148933-92-0Relevant articles and documents
Studies on the Degradation of Mevinolin and Compactin: A Formal Route to Semisynthetic Analogues
Clive, D. L. J.,Zhang, Chengzhi
, p. 1413 - 1427 (2007/10/02)
Procedures are described for degrading mevinolin (1a) and compactin (1b) into the enone 2, which is a substance that has been elaborated into 1a, 1b, and 3-ethylcompactin (1c).Consequently, 2 serves as an advanced intermediate for the construction of semi
Formal Preparation of Semisynthetic Analogues of the Cholesterol-lowering Agent Mevinolin
Clive, Derrick L. J.,Zhang, Chengzhi
, p. 647 - 649 (2007/10/02)
The cholesterol-lowering agent mevinolin 1 has been degraded to the enone 4, which had previously been synthesized and converted into mevinolin 1, compactin 2 and 3-ethylcompactin 3.