148934-27-4

Upstream product

• 58754-95-3 N-(2,2-dimethoxyethyl)-p-toluenesulfonamide 
• 168776-05-4 10,11-dihydro-10-hydroxy-3,4-dimethoxy-6,7-methylenedioxy-dibenz(b,f)oxepine 
• 168776-00-9 2-(2-bromo-3,4-dimethoxybenzyl)-2-(2-methoxymethoxy-3,4-methylenedioxyphenyl)-1,3-dithiane 
• 147919-64-0 10,11-dihydro-3,4-dimethoxy-6,7-methylenedioxy-dibenz(b,f)oxepin-10-one 
• 147919-63-9 2-(2-methoxymethoxy-3,4-methylenedioxyphenyl)-1,3-dithiane 
• 7477-50-1 2-bromo-1-chloromethyl-3,4-dimethoxy-benzene 

Relevant academic research and scientific papers

Total synthesis of cularine alkaloids via dibenzoxepines as key intermediates

The total synthesis of several cularine alkaloids (cularine, oxocularine, dioxocularine and 4-hydroxycularine) via 10,11-dihydrodibenz(b,f)oxepin-10-ones as key intermediates is reported.

Synthesis of α-Hydroxy-Tetradehydrocularines

The first total synthesis of an α-hydroxytetradehydrocularine is described.The synthesis was based on the construction of a dibenzoxepinone followed by assembly of the isoquinoline heteroring.As a result, the structure of the alkaloid linaresine should be