148960-31-0

Basic information

• Product Name: Benzenepropanoyl chloride, 3-fluoro-
• Synonyms: Benzenepropanoyl chloride, 3-fluoro-;3-(3-fluorophenyl)propanoyl chloride
• CAS NO: 148960-31-0
• Molecular Formula: C₉H₈ClFO
• Molecular Weight: 186.6106232
• Mol File: 148960-31-0.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 242.6±23.0 °C(Predicted)
• Appearance: /
• Density: 1.231±0.06 g/cm3(Predicted)
• CAS DataBase Reference: Benzenepropanoyl chloride, 3-fluoro-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenepropanoyl chloride, 3-fluoro-(148960-31-0)
• EPA Substance Registry System: Benzenepropanoyl chloride, 3-fluoro-(148960-31-0)

Safety Data

• Hazardous Substances Data: 148960-31-0(Hazardous Substances Data)

Upstream product

• 458-45-7 3-(3-fluorophenyl)propionic acid 

Downstream Products

• 1542259-58-4 methyl (2Z)-3-[3-(3-fluorophenyl)propanamido]but-2-enoate 
• 1542258-11-6 3-(3-fluoro-4-morpholinophenyl)-2-(3-fluorophenylethyl)-6-methylpyrimidin-4(3H)-one 
• 245070-85-3 3-(3-fluorophenyl)propanal 
• 700-84-5 5-fluoro-1-indanone 

Relevant articles and documents

Carboxy Group as a Remote and Selective Chelating Group for C?H Activation of Arenes

The first example of carboxy group assisted, remote-selective C(sp2)?H activation with a PdII catalyst has been developed and proceeds through a possible κ2 coordination of the carboxy group, thus suppressing the ortho-C?H activation through κ1 coordination. Besides meta-C?H olefination, direct meta-arylation of hydrocinnamic acid derivatives with low-cost aryl iodides has been achieved for the first time. These findings may motivate the exploration of novel reactivities of the carboxy assisted C?H activation reactions with intriguing selectivities.

Nitrogenous Heterocyclic Derivatives And Their Application In Drugs

The present invention relates to the field of medicine, provided herein are novel nitrogenous heterocyclic compounds, their preparation methods and their uses as drugs, especially for treatment and prevention of tissue fibrosis. Also provided herein are pharmaceutically acceptable compositions comprising the nitrogenous heterocyclic compounds and the uses of the compositions in the treatment of human or animal tissue fibrosis, especially for human or animal renal interstitial fibrosis, glomerular sclerosis, liver fibrosis, pulmonary fibrosis, peritoneal fibrosis, myocardial fibrosis, dermatofibrosis, postsurgical adhesion, benign prostatic hyperplasia, skeletal muscle fibrosis, scleroderma, multiple sclerosis, pancreatic fibrosis, cirrhosis, myosarcoma, neurofibroma, pulmonary interstitial fibrosis, diabetic nephropathy, alzheimer disease or vascular fibrosis.

Cross-coupling of remote meta -c-h bonds directed by a u-shaped template

meta-C-H arylation and methylation of 3-phenylpropanoic acid and phenolic derivatives were developed using an easily removable nitrile template. The combination of a weakly coordinating U-shaped template and mono-protected amino acid ligand was crucial fo