148981-06-0

Upstream product

• 6066-82-6 1-hydroxy-pyrrolidine-2,5-dione 
• 1155-62-0 N-benzyloxycarbonyl-L-glutamic acid 
• 501-53-1 benzyl chloroformate 
• 56-86-0 L-glutamic acid 

Downstream Products

• 219959-99-6 (S)-2-[(S)-2-{(S)-2-Benzyloxycarbonylamino-4-[(S)-1,3-bis-((S)-1,3-bis-ethoxycarbonyl-propylcarbamoyl)-propylcarbamoyl]-butyrylamino}-4-((S)-1,3-bis-ethoxycarbonyl-propylcarbamoyl)-butyrylamino]-pentanedioic acid diethyl ester 
• 219959-95-2 ((S)-1,3-Bis-dibenzylcarbamoyl-propyl)-carbamic acid benzyl ester 
• 219959-96-3 (S)-2-Amino-pentanedioic acid bis-dibenzylamide 
• 65148-67-6 N_.N'-(N-benzyloxycarbonyl-L-glutamoyl)-bis-L-glutamic acid tetraethyl ester 

Relevant academic research and scientific papers

CONTRAST AGENTS ENDOWED WITH HIGH RELAXIVITY

The present invention relates to a novel class of paramagnetic ion-based contrast agents of formula (I), wherein a chelating backbone moiety is highly functionalized by the presence of one or more polyhdroxylated chain, that show a pharmacokinetic profile analogous to that of the commonly used T1-general extravascular agents (NSA) but are further characterized by a higher relaxivity.

The Synthesis of Chiral Dendrimeric Molecules Based on Amino Acid Repeat Units

The use of simple natural products for the synthesis of chiral dendrimeric molecules is discussed. The synthesis of dendrimeric poly-L-aspartic acid, poly-L-glutamic acid and poly-L-lysine is reported.