148988-28-7 Usage
Description
27-Hydroxy-7-keto Cholesterol is a cytostatic sterol, which is an alcohol derivative of 27-Carboxy-7-Ketocholesterol. It plays a significant role in the treatment of cancer and other conditions associated with rapidly growing cells.
Uses
Used in Pharmaceutical Industry:
27-Hydroxy-7-keto Cholesterol is used as a cytostatic agent for the treatment of cancer and other conditions associated with rapidly growing cells. It helps in controlling the unregulated cell growth and proliferation, making it a valuable compound in the development of cancer therapies.
Used in Research and Development:
27-Hydroxy-7-keto Cholesterol is also used in research and development for understanding the underlying mechanisms of cell growth and proliferation. This knowledge can contribute to the discovery of new therapeutic approaches and the improvement of existing treatments for various diseases.
Check Digit Verification of cas no
The CAS Registry Mumber 148988-28-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,8,9,8 and 8 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 148988-28:
(8*1)+(7*4)+(6*8)+(5*9)+(4*8)+(3*8)+(2*2)+(1*8)=197
197 % 10 = 7
So 148988-28-7 is a valid CAS Registry Number.
148988-28-7Relevant articles and documents
Optimal TBHP allylic oxidation of Δ5 - Steroids catalyzed by dirhodium caprolactamate
Choi, Hojae,Doyle, Michael P.
, p. 5349 - 5352 (2007)
Dirhodium caprolactamate is the most efficient catalyst for the oxidation of Δ5-steroids to 7-keto-Δ5-steroids by 70% tert-butyl hydroperoxide in water (T-HYDRO). Isolated product yields range from 38 to 87%.