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148988-28-7

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148988-28-7 Usage

Description

27-Hydroxy-7-keto Cholesterol is a cytostatic sterol, which is an alcohol derivative of 27-Carboxy-7-Ketocholesterol. It plays a significant role in the treatment of cancer and other conditions associated with rapidly growing cells.

Uses

Used in Pharmaceutical Industry:
27-Hydroxy-7-keto Cholesterol is used as a cytostatic agent for the treatment of cancer and other conditions associated with rapidly growing cells. It helps in controlling the unregulated cell growth and proliferation, making it a valuable compound in the development of cancer therapies.
Used in Research and Development:
27-Hydroxy-7-keto Cholesterol is also used in research and development for understanding the underlying mechanisms of cell growth and proliferation. This knowledge can contribute to the discovery of new therapeutic approaches and the improvement of existing treatments for various diseases.

Check Digit Verification of cas no

The CAS Registry Mumber 148988-28-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,8,9,8 and 8 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 148988-28:
(8*1)+(7*4)+(6*8)+(5*9)+(4*8)+(3*8)+(2*2)+(1*8)=197
197 % 10 = 7
So 148988-28-7 is a valid CAS Registry Number.

148988-28-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name 27-Hydroxy-7-keto Cholesterol

1.2 Other means of identification

Product number -
Other names (3S,8S,9S,10R,13R,14S,17R)-3-hydroxy-17-[(2R)-7-hydroxy-6-methylheptan-2-yl]-10,13-dimethyl-1,2,3,4,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-7-one

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:148988-28-7 SDS

148988-28-7Upstream product

148988-28-7Downstream Products

148988-28-7Relevant articles and documents

Optimal TBHP allylic oxidation of Δ5 - Steroids catalyzed by dirhodium caprolactamate

Choi, Hojae,Doyle, Michael P.

, p. 5349 - 5352 (2007)

Dirhodium caprolactamate is the most efficient catalyst for the oxidation of Δ5-steroids to 7-keto-Δ5-steroids by 70% tert-butyl hydroperoxide in water (T-HYDRO). Isolated product yields range from 38 to 87%.

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