148990-17-4

Basic information

• Product Name: 4-(4-Methoxyphenyl)-2-(Methylsulfanyl)pyriMidine
• Synonyms: 4-(4-Methoxyphenyl)-2-(Methylsulfanyl)pyriMidine;4-(4-Methoxyphenyl)-2-(Methylthio)pyriMidine
• CAS NO: 148990-17-4
• Molecular Formula: C₁₂H₁₂N₂OS
• Molecular Weight: 232.30148
• Mol File: 148990-17-4.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• CAS DataBase Reference: 4-(4-Methoxyphenyl)-2-(Methylsulfanyl)pyriMidine(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(4-Methoxyphenyl)-2-(Methylsulfanyl)pyriMidine(148990-17-4)
• EPA Substance Registry System: 4-(4-Methoxyphenyl)-2-(Methylsulfanyl)pyriMidine(148990-17-4)

Safety Data

• Hazardous Substances Data: 148990-17-4(Hazardous Substances Data)

Usage

General Description

4-(4-Methoxyphenyl)-2-(Methylsulfanyl)pyrimidine is a chemical compound with a molecular formula C13H12N2OS. It is a pyrimidine derivative with a methylsulfanyl group attached to the second carbon atom and a 4-methoxyphenyl group attached to the fourth carbon atom. 4-(4-Methoxyphenyl)-2-(Methylsulfanyl)pyriMidine has potential pharmaceutical applications due to its ability to act as a ligand for various biological targets such as enzymes and receptors. It can also be used as a building block in organic synthesis to create more complex molecules. Additionally, the presence of the methoxyphenyl and methylsulfanyl groups provides this compound with unique steric and electronic properties that can be exploited for medicinal and chemical research purposes.

Upstream product

• 49844-90-8 4-Chloro-2-methylthiopyrimidine 
• 5720-07-0 4-methoxyphenylboronic acid 
• 100-06-1 1-(4-methoxyphenyl)ethanone 
• 18096-70-3 3-dimethylamino-4'-methoxyacrylophenone 
• 17356-08-0 thiourea 
• 74-88-4 methyl iodide 
• 5751-20-2 2-Methylthiouracil 
• 82303-13-7 (4-methoxyphenyl)zinc(II) bromide 
• 104-92-7 1-bromo-4-methoxy-benzene 
• 5751-20-2 2-(methylsulfanyl)pyrimidin-4-ol 
• 75634-04-7 2-chloro-4-(p-methoxyphenyl)pyrimidine 
• 5188-07-8 sodium thiomethoxide 
• 154499-77-1 2-methylthio-4-pyrimidinyl triflate 

Downstream Products

• 1388177-46-5 4-(4-methoxyphenyl)-2-(3,4,5-trimethoxyphenyl)pyrimidine 
• 1388177-42-1 2-(3-fluoro-4-methoxyphenyl)-4-(4-methoxyphenyl)pyrimidine 
• 1388177-44-3 2-(benzo[d][1,3]dioxol-5-yl)-4-(4-methoxyphenyl)pyrimidine 
• 1360780-45-5 2,4-bis(4-methoxyphenyl)pyrimidine 

Relevant articles and documents

Design, synthesis, and preliminary bioactivity evaluation of N-benzylpyrimidin-2-amine derivatives as novel histone deacetylase inhibitor

Histone deacetylase (HDAC) inhibitors have been identified for the treatment of cancer. Lately, we designed and synthesized a series of substituted N-benzylpyrimidin-2-amine derivatives as potent HDAC inhibitors. In vitro HDAC inhibitory activities and an

Cobalt-catalyzed C-SMe bond activation of heteroaromatic thioethers

Cobalt-catalyzed activation of methylthio-substituted N-heterocycles facilitates either cross-coupling reactions with aryl- or benzylzinc compounds or synthesis of the corresponding zinc compounds.

New air-stable catalysts for general and efficient Suzuki-Miyaura cross-coupling reactions of heteroaryl chlorides

New air-stable PdCl2{ PtBu2(p-R-Ph)} 2 (R = H, NMe2, CF3,) complexes represent simple, general, and efficient catalysts for the Suzuki-Miyaura cross-coupling reactions of aryl halides including five-membered heteroaryl halides and heteroatom-substituted six-membered heteroaryl chlorides with a diverse range of arylboronic acids. High product yields (89-99% isolated yields) and turn-over-numbers (10 000 TON) are observed.