14903-90-3

Basic information

• Product Name: 3-BROMO-2-FUROIC ACID
• Synonyms: 3-Bromofuran-2-carboxylic acid;2-Furancarboxylic acid,3-broMo-
• CAS NO: 14903-90-3
• Molecular Formula: C₅H₃BrO₃
• Molecular Weight: 190.99
• Product Categories: Heterocycles series
• Mol File: 14903-90-3.mol

Chemical Properties

• Melting Point: 127-129 °C
• Boiling Point: 278 °C at 760 mmHg
• Flash Point: 121.9 °C
• Appearance: /
• Density: 1.891 g/cm³
• Vapor Pressure: 0.0021mmHg at 25°C
• Refractive Index: 1.571
• Storage Temp.: 2-8°C
• PKA: 2.77±0.20(Predicted)
• CAS DataBase Reference: 3-BROMO-2-FUROIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 3-BROMO-2-FUROIC ACID(14903-90-3)
• EPA Substance Registry System: 3-BROMO-2-FUROIC ACID(14903-90-3)

Safety Data

• Hazard Codes: Xn
• Statements: 20/21/22-36/37/38
• Safety Statements: 22-26-36/37/39
• Hazardous Substances Data: 14903-90-3(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
3-BROMO-2-FUROIC ACID is used as a building block in the production of pharmaceuticals, agrochemicals, and other industrial chemicals. Its unique structure allows for the synthesis of a wide range of organic compounds, contributing to the development of new products in these industries.
Used in Chemical Research:
3-BROMO-2-FUROIC ACID is used as a reagent in chemical research, facilitating the study of various chemical reactions and processes. Its presence in experiments can provide insights into the behavior of different chemical systems and help researchers understand the underlying mechanisms.
Used in Pharmaceutical Production:
3-BROMO-2-FUROIC ACID is used as a key component in the synthesis of pharmaceuticals. Its unique properties enable the development of new drugs with potential therapeutic applications, improving the treatment options for various medical conditions.
Used in Agrochemical Production:
3-BROMO-2-FUROIC ACID is used in the production of agrochemicals, such as pesticides and herbicides. Its incorporation into these products can enhance their effectiveness in controlling pests and weeds, contributing to increased crop yields and agricultural productivity.
Despite its low toxicity and lack of significant environmental or health hazards, it is essential to handle 3-BROMO-2-FUROIC ACID with care and follow proper safety protocols during its use in various applications.

InChI:InChI=1/C5H3BrO3/c6-3-1-2-9-4(3)5(7)8/h1-2H,(H,7,8)

Downstream Products

• 478488-70-9 5-(3-bromo-furan-2-yl)-3-(4-chloro-phenyl)-[1,2,4]-oxadiazole 
• 71237-37-1 3-Phenyl-2-furoyl chloride 
• 169772-63-8 3-phenyl-2-furoic acid 
• 71237-44-0 methyl 3-phenyl-2-furoate 
• 1357588-68-1 1-(3-bromofuran-2-yl)-2-{[4-iodo-3-(trifluoromethoxy)phenyl]hydrazono}butane-1,3-dione 
• 1357588-59-0 1-(3-bromofuran-2-yl)-2-{[2-fluoro-4-(1H-pyrazol-1-yl)phenyl]hydrazono}butane-1,3-dione 
• 1357588-53-4 1-(3-bromofuran-2-yl)-2-{[3-(trifluoromethyl)phenyl]hydrazono}butane-1,3-dione 
• 32460-07-4 ethyl 3-bromofuran-2-carboxylate 
• 1357588-63-6 3-(1-phenyl-1H-pyrazol-5-yl)-1-[4-(1H-pyrazol-1-yl)-2-(2,2,2-trifluoroethoxy)phenyl]-6,7-dihydrofuro[3,2-c]pyridazin-4(1H)-one 
• 1357588-62-5 3-(1-phenyl-1H-pyrazol-5-yl)-1-[4-(1H-pyrazol-1-yl)-2-(2,2,2-trifluoroethoxy)phenyl]furo[3,2-c]pyridazin-4(1H)-one 
• 1357588-61-4 1-[2-fluoro-4-(1H-pyrazol-1-yl)phenyl]-3-(1-phenyl-1H-pyrazol-5-yl)-6,7-dihydrofuro[3,2-c]pyridazin-4(1H)-one 
• 1357588-58-9 1-[2-fluoro-4-(1H-pyrazol-1-yl)phenyl]-3-(1-phenyl-1H-pyrazol-5-yl)furo[3,2-c]pyridazin-4(1H)-one 
• 1357588-60-3 3-acetyl-1-[2-fluoro-4-(1H-pyrazol-1-yl)phenyl]furo[3,2-c]pyridazin-4(1H)-one 
• 1357588-57-8 3-acetyl-1-[3-(trifluoromethyl)phenyl]-6,7-dihydrofuro[3,2-c]pyridazin-4(1H)-one 

Relevant articles and documents

Substituted 3-aryl-5-aryl-[1,2,4]-oxadiazoles and analogs as activators of caspases and inducers of apoptosis and the use thereof

The present invention is directed to substituted 3-aryl-5-aryl-[1,2,4]-oxadiazoles and analogs thereof, represented by the Formula I: wherein Ar1, Ar3, A, B and D are defined herein. The present invention also relates to the discovery that compounds having Formula I are activators of caspases and inducers of apoptosis. Therefore, the activators of caspases and inducers of apoptosis of this invention may be used to induce cell death in a variety of clinical conditions in which uncontrolled growth and spread of abnormal cells occurs.