14906-56-0

Basic information

• Product Name: N-(1-hydroxypyridin-4(1H)-ylidene)acetamide
• CAS NO: 14906-56-0
• Molecular Formula: C₇H₈N₂O₂
• Molecular Weight: 152.1506
• Mol File: 14906-56-0.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 250.3°C at 760 mmHg
• Flash Point: 105.2°C
• Density: 1.2g/cm³
• Vapor Pressure: 0.00346mmHg at 25°C
• Refractive Index: 1.561
• CAS DataBase Reference: N-(1-hydroxypyridin-4(1H)-ylidene)acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(1-hydroxypyridin-4(1H)-ylidene)acetamide(14906-56-0)
• EPA Substance Registry System: N-(1-hydroxypyridin-4(1H)-ylidene)acetamide(14906-56-0)

Safety Data

• Hazardous Substances Data: 14906-56-0(Hazardous Substances Data)

Upstream product

• 3535-75-9 4-aminopyridine-1-oxide 
• 108-24-7 acetic anhydride 
• 5221-42-1 4-acetylaminopyridine 
• 1398-61-4 chitin 
• 504-24-5 4-aminopyridine 
• 14150-95-9 2-aminopyridine N-oxide 
• 830-03-5 4-nitrophenol acetate 

Downstream Products

• 856846-18-9 N-(1-acetyl-[4]piperidyl)-acetamide 
• 13035-19-3 4-aminopiperidine 

Relevant articles and documents

A new transformation of aminopyridines upon diazotization in acetonitrile with the formation of N-pyridinylacetamides

Diazotization of aminopyridines upon treatment with NaNO2 and H3PO4 in acetonitrile led to the formation of N-pyridinylacetamides. This reaction constitutes a convenient and general preparative method for the synthesis of 2-, 3-, and 4-N-pyridinylacetamides under mild conditions in good yields. The in situ oxidation of the thus obtained N-pyridinylacetamides with hydrogen peroxide gave good yields of pyridinylacetamide N-oxides.

New description of substituent effect on electronic spectra by means of substituent constants-VI. Ultraviolet spectra of 4-substituted pyridine N-oxides and blue shifted iodine bands of their EDA complexes with iodine

Electronic spectra of 4-substituted pyridine N-oxides and their EDA complexes with iodine were studied.The substituent effect on the near u.v. 1A1 intramolecular CT bands of the N-oxides and on the blue shifted iodine bands caused by CT complex formation are discussed in terms of a general equation, theoretically derived in order to describe the substituent effect on electronic spectra by means of substituent constants.The results are quite successful and supported by semi-empirical SCFMO-Cl calculations.Based on the results mentioned above, the character of n-? type N-oxide-iodine CT complexes is also examined.The complex formation constants(log K) and pKa values of the N-oxides correlate especially well, indicating that the CT interaction mechanism cannot be neglected in proton addition reactions such as hydrogen bonding and pKa values.