149116-21-2Relevant academic research and scientific papers
Synthesis and analgesic activities of urea derivatives of α-amino-N-pyridyl benzene propanamide
Sartori, E.,Camy, F.,Teulon, J. M.,Camborde, F.,Meignen, J.,at el.
, p. 431 - 440 (2007/10/02)
New urea L-phenyl alanine derivatives of 4-aminopyridine have been synthesized and evaluated for analgesic activity with the PBQ writhing test in mice and the Randall-Selitto test in rats.Potent oral activity (ID50 10 mg/kg) and good tolerance were foun
Analgesic α-amino-N-pyridylbenzenepropanamide derivatives and pharmaceutical compositions containing them
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, (2008/06/13)
The present invention relates to the derivatives of the formula STR1 in the (S) configuration, to their addition salts and to their use in therapy, especially as drugs with analgesic properties.
