1491841-75-8Relevant articles and documents
Modular isoquinoline synthesis using catalytic enolate arylation and in situ functionalization
Pilgrim, Ben S.,Gatland, Alice E.,McTernan, Charlie T.,Procopiou, Panayiotis A.,Donohoe, Timothy J.
, p. 6190 - 6193 (2014/01/17)
A methyl ketone, an aryl bromide, an electrophile, and ammonium chloride were combined in a four-component, three-step, and one-pot coupling procedure to furnish substituted isoquinolines in overall yields of up to 80%. This protocol utilizes the palladiu