149227-04-3

Usage

Uses

Used in Organic Synthesis:
1-(3-bromopyridin-4-yl)ethan-1-ol is used as a building block in the synthesis of various organic compounds. Its unique structure allows it to participate in a range of chemical reactions, making it a versatile component in the creation of new molecules.
Used in Pharmaceutical Research:
In the pharmaceutical industry, 1-(3-bromopyridin-4-yl)ethan-1-ol is utilized as a key intermediate in the development of new drugs. Its ability to interact with biological systems and undergo chemical modifications makes it a promising candidate for the design and synthesis of innovative therapeutic agents.
Used in Chemical Reactions:
1-(3-bromopyridin-4-yl)ethan-1-ol is employed as a reactant in various chemical reactions, such as substitution, addition, and condensation reactions. Its reactivity and structural features enable the formation of diverse products with potential applications in different fields.
Used in Material Development:
1-(3-bromopyridin-4-yl)ethan-1-ol is also used in the development of new materials, thanks to its ability to form stable complexes and interact with other molecules. This property makes it a valuable component in the creation of advanced materials with specific properties and functions.

Upstream product

• 626-55-1 3-Bromopyridine 
• 75-07-0 acetaldehyde 
• 75-16-1 methylmagnesium bromide 
• 70201-43-3 3-bromo-pyridine-4-carbaldehyde 

Relevant academic research and scientific papers

Scalable and Straightforward Synthesis of All Isomeric (Cyclo)alkylpiperidines

An efficient approach towards introducing (cyclo)alkyl substituents at C-2, C-3 or C-4 positions of the piperidine ring was described. The method relied on the straightforward two-step reaction sequence based on the formal sp3–sp3 re

PYRIDINYL PYRAZOLES AS MODULATORS OF RORyT

The present invention comprises compounds of Formula I. wherein: R1, R3, R4, R5, R6, and Q are defined in the specification. The invention also comprises a method of treating or ameliorating a ROR-γ-t mediated syndrome, disorder or disease, including wherein the syndrome, disorder or disease is selected from the group consisting of rheumatoid arthritis, psoriatic arthritis, and psoriasis. The invention also comprises a method of modulating RORγt activity in a mammal by administration of a therapeutically effective amount of at least one compound of Formula I.

6-AMINOPYRIDIN-3-YL PYRAZOLES AS MODULATORS OF RORgT

The present invention comprises compounds of Formula I. wherein: R1, Q, R3, R4, R5, R6, A1, and A2 are defined in the specification. The invention also comprises a method of treating or ameliorating a ROR-γ-t mediated syndrome, disorder or disease, including wherein the syndrome, disorder or disease is selected from the group consisting of rheumatoid arthritis, psoriatic arthritis, and psoriasis. The invention also comprises a method of modulating RORγt activity in a mammal by administration of a therapeutically effective amount of at least one compound of Formula I.

ALDOSTERONE SYNTHASE INHIBITORS

The present invention relates to compounds of formula (I): and pharmaceutically acceptable salts thereof, wherein R1, R2. R3, R4, R5, R6, R7, W, Y, m and n are as defined herein. The invention also relates to pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of various diseases and disorders, processes for preparing these compounds and intermediates useful in these processes.

BENZOXAZOLONE DERIVATIVES AS ALDOSTERONE SYMTHASE INHIBITORS

The present invention provides a compound of formula (I) a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical comp

REGIOSELECTIVE ORTHO-LITHIATION OF HALOPYRIDINES. SYNTHESES OF ORTHO-DISUBSTITUTED PYRIDINES AND A CONVENIENT GENERATION OF 3,4-PYRIDYNE

The regioselective ortho-lithiation of 3-chloro- (4), 3-fluoro- (7), 3-bromo- (10), 2-chloro- (22), and 4-chloropyridine (25) with lithium diisopropylamide affords, after quenching with various electrophiles, the corresponding ortho-disubstituted pyridine