149228-60-4 Usage
General Description
1-(1'-cyanoribofuranosyl)thymine is a synthetic nucleoside analog that is composed of a modified thymine base linked to a ribose sugar with a cyanide group attached to the ribose ring. It is often used in the study of nucleic acid structure and function and has been implicated in potential anti-viral and anti-cancer applications due to its ability to interfere with DNA replication and transcription. The compound is also being explored as a possible component of nucleic acid-based therapeutics. Its unique structure and activity make it a valuable tool for researchers in the field of nucleic acid chemistry and biology.
Check Digit Verification of cas no
The CAS Registry Mumber 149228-60-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,9,2,2 and 8 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 149228-60:
(8*1)+(7*4)+(6*9)+(5*2)+(4*2)+(3*8)+(2*6)+(1*0)=144
144 % 10 = 4
So 149228-60-4 is a valid CAS Registry Number.
149228-60-4Relevant articles and documents
Synthesis and structure determination of the first 1'-C-cyano-β-D-nucleosides
Uteza,Chen,Le Quan Tuoi,Descotes,Fenet,Grouiller
, p. 8579 - 8588 (1993)
The 1'-cyano-2',3'-D-unsaturated nucleoside 8 was synthesised according to the following steps. Photobromination of the ribofuranosyl cyanide 1 using N-bromosuccinimide (NBS) as a radical source gave the two isomers of the new C-1 gem disubstituted sugar
