Synthesis and structure determination of the first 1'-C-cyano-β-D-nucleosides

DOI: 10.1016/S0040-4020(01)96264-7

Source and publish data:

Tetrahedron p. 8579 - 8588 (1993)

Update date:2022-07-30

Topics:

Authors:

Uteza Uteza

Chen Chen

Le Quan Tuoi

Descotes

Fenet Fenet

Grouiller

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Article abstract of DOI:10.1016/S0040-4020(01)96264-7

The 1'-cyano-2',3'-D-unsaturated nucleoside 8 was synthesised according to the following steps. Photobromination of the ribofuranosyl cyanide 1 using N-bromosuccinimide (NBS) as a radical source gave the two isomers of the new C-1 gem disubstituted sugar

Full text of DOI:10.1016/S0040-4020(01)96264-7

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