149244-09-7Relevant academic research and scientific papers
Intramolecular copper(I)-catalyzed 1,3-dipolar cycloaddition of azido-alkynes: Synthesis of triazolo-benzoxazepine derivatives and their biological evaluation
Chandrasekhar, Srivari,Seenaiah, Mallikanti,Kumar, Abhishek,Reddy, Chada Raji,Mamidyala, Suman Kumar,Kumar, Chityal Ganesh,Balasubramanian, Sridhar
supporting information; experimental part, p. 806 - 808 (2011/03/20)
Synthesis of a series of [1,2,3] triazolo [5,1-c] [1,4]benzoxazepine derivatives have been accomplished by the intramolecular Cu(I)-catalyzed cycloaddition of azido-alkynes derived from salicylaldehyde. The biological profile of these heterocyclic structu
Steric acceleration of intramolecular cycloaddition reactions
Orlek, Barry S.,Sammes, Peter G.,Weller, David J.
, p. 8179 - 8194 (2007/10/02)
Use of conformational constraints, induced by different ortho-substituents in 1-allyloxy-2-(substituted)methylbenzenes, where the substituent is a 1,3-dipole such as the azide or 3-oxidopyridinium group, can be employed to accelerate the 1,3-dipolar cycloaddition reaction. In this manner cycloadditions that otherwise do not proceed can be forced to react.
