1493-86-3Relevant academic research and scientific papers
From C1 to C3: Copper-Catalyzed gem-Bis(trifluoromethyl)olefination of α-Diazo Esters with TMSCF3
Hu, Jinbo,Hu, Mingyou,Liu, Qinghe,Ni, Chuanfa,Pan, Shitao,Wang, Qian,Xie, Qiqiang
, p. 8507 - 8511 (2020)
A Cu-catalyzed gem-bis(trifluoromethyl)olefination of α-diazo esters, using TMSCF3 as the only fluorocarbon source, has been developed and provides an exquisite method to access gem-bis(trifluoromethyl)alkenes. This unprecedented olefination pr
Nucleophilic Substitution of gem-Difluoroalkenes with TMSNu Promoted by Catalytic Amounts of Cs2CO3
Jiang, Ling-Feng,Ren, Bing-Tao,Li, Bin,Zhang, Guang-Yi,Peng, Yi,Guan, Zhen-Yu,Deng, Qing-Hai
supporting information, p. 6557 - 6564 (2019/06/18)
The efficient and practical nucleophilic cyanation and trifluoromethylation with appropriate trimethylsilyl nucleophiles were developed. Catalytic amounts of cheap and nontoxic Cs2CO3 were used to maintain a sufficiently high concentration of nucleophilic anion (CN- or CF3-) which could begin the catalytic cycle. The present methodologies provide diverse functionalized monofluoroalkenes bearing a cyano and trifluoromethyl group with excellent to moderate stereoselectivities.
Mild and metal-free trifluoromethylation and pentafluoroethylation of gem-difluoroalkenes with TMSCF3 and TMSCF2CF3
Jin, Guanyi,Zhang, Xuxue,Fu, Dan,Dai, Wenpeng,Cao, Song
, p. 7892 - 7899 (2015/09/15)
A direct and efficient approach for the trifluoromethylation and pentafluoroethylation of 1,1-diaryl-2,2-difluoroethenes with TMSCF3 and TMSCF2CF3 in the presence of TBAF was developed. The reactions proceeded smoothly und
Copper-catalyzed gem -difluoroolefination of diazo compounds with TMSCF3 via C-F bond cleavage
Hu, Mingyou,He, Zhengbiao,Gao, Bing,Li, Lingchun,Ni, Chuanfa,Hu, Jinbo
supporting information, p. 17302 - 17305 (2014/01/06)
A novel Cu-catalyzed gem-difluoroolefination of diazo compounds is described. This transformation starts from readily available TMSCF3 and diazo compounds, via trifluoromethylation followed by C-F bond cleavage, to afford the desired 1,1-difluoroalkene products.
On the reactions of trifluorovinylsilanes with aromatic ketones - Expected and some unexpected results
Kirij,Dontsova,Pavlenko,Yagupolskii,Tyrra,Naumann
scheme or table, p. 184 - 189 (2010/04/30)
The reactions of aromatic ketones with trialkyl(trifluorovinyl)silanes in the presence of fluoride ions were studied. The conditions for the selective addition of trialkyl(trifluorovinyl)silanes to the carbonyl function of aromatic ketones in the presence
Preparation of α- or β-trifluoromethylated vinylstannanes and their cross-coupling reactions
Jeong, In Howa,Park, Young Sam,Kim, Myong Sang,Song, Yong Sup
, p. 195 - 209 (2007/10/03)
α - or β-Trifluoromethylated vinylstannanes 1, 2a, 3 and 4 were prepared form 1,1-bis(phenylthio)-2,2,3,3,3-pentafluoropropylbenzene (5) via several steps. The cross-coupling arylation reactions of 1-4 with aryl iodides bearing a bromo, methoxy, methyl, n
