14933-25-6 Usage
Description
3-Chloro-4-hydroxy-1H-quinolin-2-one is a synthetic heterocyclic compound with the molecular formula C9H6ClNO2. It is a chlorinated derivative of 4-hydroxyquinoline, known for its versatile reactivity and pharmacological potential. 3-Chloro-4-hydroxy-1H-quinolin-2-one serves as a valuable intermediate in the synthesis of pharmaceuticals and fine chemicals, and has been studied for its potential biological activities, including anti-inflammatory, antifungal, and anticancer properties.
Uses
Used in Pharmaceutical Synthesis:
3-Chloro-4-hydroxy-1H-quinolin-2-one is used as an intermediate in the pharmaceutical industry for the synthesis of various drugs and fine chemicals. Its unique structure and reactivity make it a key component in the development of new therapeutic agents.
Used in Biological Research:
In the field of biological research, 3-Chloro-4-hydroxy-1H-quinolin-2-one is utilized for studying its potential biological activities. Its anti-inflammatory, antifungal, and anticancer properties are of particular interest, as they may contribute to the development of novel treatments for various diseases and conditions.
Used in Drug Development:
3-Chloro-4-hydroxy-1H-quinolin-2-one is used as a building block in drug development, particularly for the creation of new drugs and agrochemicals. Its versatile reactivity and pharmacological potential make it a promising candidate for the design and synthesis of innovative therapeutic agents.
Used in Agrochemical Development:
In the agrochemical industry, 3-Chloro-4-hydroxy-1H-quinolin-2-one is employed as a starting material for the development of new agrochemicals. Its potential applications in this field include the creation of novel pesticides, fungicides, and other agricultural chemicals that can improve crop protection and yield.
Check Digit Verification of cas no
The CAS Registry Mumber 14933-25-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,4,9,3 and 3 respectively; the second part has 2 digits, 2 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 14933-25:
(7*1)+(6*4)+(5*9)+(4*3)+(3*3)+(2*2)+(1*5)=106
106 % 10 = 6
So 14933-25-6 is a valid CAS Registry Number.
InChI:InChI=1/C9H6ClNO2/c10-7-8(12)5-3-1-2-4-6(5)11-9(7)13/h1-4H,(H2,11,12,13)
14933-25-6Relevant articles and documents
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George,T.,Tahilramani,R.
, p. 1007 - 1010 (1968)
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Ylides of Heterocycles, VIII. Reactions of Iodonium-Ylides with Acids
Pongratz, Erik,Kappe, Thomas
, p. 231 - 242 (2007/10/02)
The reaction of various organic and inorganic acids (HX) with iodonium ylides 2 leads to nucleophilic substitution of the iodobenzene substituent by the anion X(-) to yield the heterocycles 5.Some of them are hydrolyzed to the hydroxy compounds 3 or reduced to the starting compounds 1 under the reaction conditions.Reaction of the iodonium ylide 2b with monomethyl sulfate gives the salt 9, which with bases undergoes nucleophilic substitution to compounds 8 and 10-12, respectively, or is converted to 2b again. - Keywords: 3-Acetoxy-4-hydroxy-2-quinolones; 2-Oxoquinoline-4-olates; 3-Substituted 4-hydroxy-2-quinolones