149364-94-3

Basic information

• Product Name: tert-butyl(4-(furan-2-yl)butoxy)diphenylsilane
• Synonyms: tert-butyl(4-(furan-2-yl)butoxy)diphenylsilane
• CAS NO: 149364-94-3
• Molecular Weight: 378.587
• Mol File: 149364-94-3.mol

Chemical Properties

• CAS DataBase Reference: tert-butyl(4-(furan-2-yl)butoxy)diphenylsilane(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl(4-(furan-2-yl)butoxy)diphenylsilane(149364-94-3)
• EPA Substance Registry System: tert-butyl(4-(furan-2-yl)butoxy)diphenylsilane(149364-94-3)

Safety Data

• Hazardous Substances Data: 149364-94-3(Hazardous Substances Data)

Upstream product

• 130372-07-5 4-(tret-butyldiphenylsilyloxy)butan-1-ol 
• 110-00-9 furan 
• 149365-02-6 4-[(tert-butyldiphenylsilyl)oxy]-1-iodobutane 

Downstream Products

• 1287695-79-7 (3R,3aS,8R,10aS)-3-(tert-butyldimethylsiloxy)-8-(4-(tert-butyldiphenylsiloxy)butyl)-3a-methyl-3a,4,7,8-tetrahydro-2H-8,10a-epoxycyclohepta[e]-inden-6(3H)-one 
• 1287695-78-6 (3R,3aS,5R,5aS,8R,10aR)-3-(tert-butyldimethylsiloxy)-8-(4-(tert-butyldiphenylsiloxy)butyl)-5-hydroxy-3a-methyl-3a,4,5,5a,7,8-hexahydro-2H-8,10a-epoxycyclohepta[e]inden-6(3H)-one 
• 1287695-77-5 tert-butyl(4-(5-((4R,5S)-4-(tert-butyldimethylsiloxy)-5-methyl-5-(((2R,3S)-3-(1-(triethylsiloxy)vinyl)oxiran-2-yl)methyl)cyclopent-1-en-1-yl)furan-2-yl)butoxyl)diphenylsilane 
• 1287695-76-4 1-((2S,3R)-3-(((1S,5R)-5-(tert-butyldimethylsiloxy)-2-(5-(4-(tert-butyldiphenylsiloxy)butyl)furan-2-yl)-1-methylcyclopent-2-en-1-yl)methyl)oxiran-2-yl)ethanone 
• 1287695-75-3 (E)-5-((1S,5R)-5-(tert-butyldimethylsilyloxy)-2-(5-(4-(tert-butyldiphenylsiloxy)-butyl)furan-2-yl)-1-methylcyclopent-2-en-1-yl)pent-3-en-2-one 
• 1287695-73-1 (((1R,2S)-2-allyl-3-(5-(4-(tert-butyldiphenylsiloxy)butyl)furan-2-yl)-2-methyl-cyclopent-3-en-1-yl)oxy)(tert-butyl)dimethylsilane 
• 1287695-71-9 (1S,2R,3R)-2-allyl-3-(tert-butyldimethylsiloxy)-1-(5-(4-(tert-butyldiphenylsiloxy)-butyl)furan-2-yl)-2-methylcyclopentanol 
• 1035420-82-6 C₂₅H₃₄O₅Si 
• 738604-57-4 2-(2-hydroxyethyl)-3-hydroxyoxepane 
• 738604-50-7 5-[4-(tert-Butyl-diphenyl-silanyloxy)-butyl]-5-methoxy-5H-furan-2-one 

Relevant articles and documents

Cyclopentanone derivatives, method of synthesis and uses thereof

The present invention relates to cyclopentanone derivatives of formula (I), their method of synthesis and uses thereof. Concretely, the compounds disclosed have proved to be inhibitors of glycogen synthase kinase 3β, GSK-3 β, which is known to be involved in different disease and conditions, such as Alzheimer's disease or non-insulin dependent diabetes mellitus. The present invention also relates to pharmaceutical compositions comprising the same. Further, the present invention is directed to the use of the compounds in the manufacture of a medicament for the treatment and/or prevention of a GSK-3 mediated disease or condition.

The furan approach to oxacycles: Synthesis of medium-size 2,3-disubstituted oxacycles

We describe an efficient new approach for the synthesis of medium-size oxacycles that is based on the oxidation of a furan ring with singlet oxygen followed by an intramolecular Michael addition. This present study enlarges the scope of the furan approach strategy for the synthesis of oxepanes.