1287695-75-3

Upstream product

• 1287695-71-9 (1S,2R,3R)-2-allyl-3-(tert-butyldimethylsiloxy)-1-(5-(4-(tert-butyldiphenylsiloxy)-butyl)furan-2-yl)-2-methylcyclopentanol 
• 1287695-73-1 (((1R,2S)-2-allyl-3-(5-(4-(tert-butyldiphenylsiloxy)butyl)furan-2-yl)-2-methyl-cyclopent-3-en-1-yl)oxy)(tert-butyl)dimethylsilane 
• 78-94-4 methyl vinyl ketone 
• 1287695-82-2 (2R,3R)-2-allyl-3-(tert-butyldimethylsiloxy)-2-methylcyclopentanone 
• 26828-48-8 2-allyl-2-methyl-1,3-cyclopentanedione 
• 109120-84-5 (2S,3S)-2-allyl-3-hydroxy-2-methylcyclopentan-1-one 
• 149364-94-3 tert-butyl(4-(furan-2-yl)butoxy)diphenylsilane 

Downstream Products

• 1287695-76-4 1-((2S,3R)-3-(((1S,5R)-5-(tert-butyldimethylsiloxy)-2-(5-(4-(tert-butyldiphenylsiloxy)butyl)furan-2-yl)-1-methylcyclopent-2-en-1-yl)methyl)oxiran-2-yl)ethanone 
• 1287695-77-5 tert-butyl(4-(5-((4R,5S)-4-(tert-butyldimethylsiloxy)-5-methyl-5-(((2R,3S)-3-(1-(triethylsiloxy)vinyl)oxiran-2-yl)methyl)cyclopent-1-en-1-yl)furan-2-yl)butoxyl)diphenylsilane 
• 1287695-78-6 (3R,3aS,5R,5aS,8R,10aR)-3-(tert-butyldimethylsiloxy)-8-(4-(tert-butyldiphenylsiloxy)butyl)-5-hydroxy-3a-methyl-3a,4,5,5a,7,8-hexahydro-2H-8,10a-epoxycyclohepta[e]inden-6(3H)-one 
• 1287695-79-7 (3R,3aS,8R,10aS)-3-(tert-butyldimethylsiloxy)-8-(4-(tert-butyldiphenylsiloxy)butyl)-3a-methyl-3a,4,7,8-tetrahydro-2H-8,10a-epoxycyclohepta[e]-inden-6(3H)-one 

Relevant academic research and scientific papers

Formal Total Synthesis of (+)-Cortistatins A and J

An efficient formal total synthesis of (+) cortistatins A and J has been accomplished, by exploiting a highly diastereoselective intramolecular [4+3] cycloaddition of epoxy enolsilanes as the key reaction to construct rings B and C of the cortistatins in

An expeditious asymmetric synthesis of the pentacyclic core of the cortistatins by an intramolecular (4+3) cycloaddition

A concise, asymmetric synthesis of the pentacyclic framework of the cortistatins has been accomplished in 12 steps from commercially available starting materials, employing a highly diastereoselective intramolecular (4+3) cycloaddition of epoxy enolsilane