149402-97-1Relevant academic research and scientific papers
Glycosyl isoxazole compound, preparation method thereof and bactericide
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Paragraph 0122-0124; 0127; 0178-0179; 0182; 0185, (2021/04/07)
The invention relates to the technical field of bactericidal materials, and particularly relates to a glycosyl isoxazole compound, a preparation method thereof and a bactericide. The glycosyl isoxazole compound has a structural general formula shown in the description, wherein R1 is selected from any one of substituted or unsubstituted aromatic groups, and R2 is selected from any one of H, acetyl, benzyl and propargyl. According to the invention, a natural saccharide compound is adopted as the framework, the safety is provided, the toxicity is low, the selectivity is high, residue is not easily generated, the environmental compatibility is good, the active group isoxazole structure is further introduced, and the obtained glycosyl isoxazole compound has advantages of safety, high efficiency, low toxicity, low residue, broad spectrum, resistance generation resistance resistance resistance generation resistance and the like, and further has excellent bactericidal activity.
Nafion-H mediated selective deprotection of terminal isopropylidene acetals and trityl ethers. Application in the synthesis of a substituted piperidone
Rawal, Girish K.,Rani, Shikha,Kumar, Amit,Vankar, Yashwant D.
, p. 9117 - 9120 (2007/10/03)
A facile chemoselective hydrolysis of terminal isopropylidene acetals has been achieved in good to excellent yields within 2-4 h using Nafion-H in methanol at ambient temperature. This procedure has been employed to synthesize a substituted piperidone der
A one-pot strategy for synthesis of 5-O-(α-D-Arabinofuranosyl)-6-O-(β-D-galactofuranosyl)-D- galactofuranose present in motif E of the Mycobacterium tuberculosis cell wall
Wang, Hairong,Ning, Jun
, p. 2521 - 2524 (2007/10/03)
5-O-(α-D-Arabinofuranosyl)-6-O-(β-D-galactofuranosyl)-D- galactofuranose 6 present in motif E of the Macobacterium tuberculosis cell wall has been regio- and stereospecifically synthesized using 3-O-benzoyl-1,2-O-isopropylidine-α-D-galactofuranose (10) as the glycosyl acceptor by the trichloroacetamidate method in a one-pot manner. The diol glycosyl acceptor 10 was smoothly derived from 1,2:5,6-di-O-isopropylidene-α-D-galactofuranose (8) by 3-O-benzoylation and then selective 5,6-O-deacetonation. The preparation of 8 was greatly improved by increasing the ratio of DMF to acetone and using a solid-supported catalyst.
