14950-73-3

Upstream product

• 693-03-8 n-butyl magnesium bromide 
• 374559-49-6 Toluene-4-sulfonic acid (2S,3S)-3-(3,5-dimethoxy-phenyl)-2-methyl-butyl ester 
• 199388-20-0 3'S-(3,5-dimethoxyphenyl)-2'S-methyl-1-butanol 
• 214466-03-2 (2S,3S)-3-(3,5-Dimethoxy-phenyl)-1-((1S,5R,7R)-10,10-dimethyl-3,3-dioxo-3λ⁶-thia-4-aza-tricyclo[5.2.1.0^1,5]dec-4-yl)-2-methyl-butan-1-one 
• 214466-02-1 N-[(E)-2-methyl-3-{3,5-dimethoxyphenyl}-2-propenoyl]-bornane-10,2-sultam 
• 214466-00-9 3'S-(3,5-dimethoxyphenyl)-2'S-methylbutanoic acid 

Downstream Products

• 214770-69-1 5-((1S,2R)-1,2-Dimethyl-heptyl)-benzene-1,3-diol 

Relevant academic research and scientific papers

Enantioselective synthesis of 11-hydroxy-(1′S,2′R)-dimethylheptyl-Δ8-THC, a very potent CB1 agonist

An enantioselective synthesis of the (1S,2R)-dimethylheptyl cannabinoid side chain has been developed and employed in the synthesis of 11-hydroxy-(1′S,2′R)-dimethylheptyl-Δ8-THC, one of the most potent traditional cannabinoids known. The synthesis involves a highly stereoselective addition of dimethylcopperlithium to an enoyl sultam which incorporates Opplozer's auxiliary.