149506-54-7Relevant academic research and scientific papers
Potent novel nonsteroidal androgen antagonists with a phthalimide skeleton
Miyachi, Hiroyuki,Azuma, Akihiko,Kitamoto, Takuya,Hayashi, Kozue,Kato, Shigeaki,Koga, Masafumi,Sato, Bunzo,Hashimoto, Yuichi
, p. 1483 - 1488 (1997)
Anti-androgenic activity of various phthalimide analogs was evaluated based on inhibition of androgen-induced activation of nuclear androgen receptor (CAT assay) and on growth inhibition of the androgen-dependent clonal cell line SC-3. Some compounds showed very potent androgen-antagonistic activity.
Cyclic imino derivatives and pharmaceutical compositions containing them
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, (2008/06/13)
The invention relates to cyclic imino compounds which have, inter alia, valuable pharmacological properties, especially inhibitory effects on cell aggregation, pharmaceutical compositions which contain these compounds and processes for preparing them.
