Potent novel nonsteroidal androgen antagonists with a phthalimide skeleton

DOI: 10.1016/S0960-894X(97)00249-7

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 1483 - 1488 (1997)

Update date:2022-07-29

Topics:

Authors:

Miyachi, Hiroyuki

Azuma, Akihiko

Kitamoto, Takuya

Hayashi, Kozue

Kato, Shigeaki

Koga, Masafumi

Sato, Bunzo

Hashimoto, Yuichi

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0960-894X(97)00249-7

Anti-androgenic activity of various phthalimide analogs was evaluated based on inhibition of androgen-induced activation of nuclear androgen receptor (CAT assay) and on growth inhibition of the androgen-dependent clonal cell line SC-3. Some compounds showed very potent androgen-antagonistic activity.

Full text of DOI:10.1016/S0960-894X(97)00249-7

Products guided by the article

Product name:1H-Isoindole-1,3(2H)-dione, 2-[(2,3-dihydro-1H-inden-2-yl)methyl]-

Cas No:149506-54-7

R&D Labs maybe for 149506-54-7

FUJIAN SHANSHUI CHEMICAL CORP.LTD.

Contact:+86-151-59920036

Address:Jinqiao Gareden, jo@fj-xinyi.com
Zibo Ocean International Trade Co.,Ltd(expird)

Contact:+86 533 5160706

Address:1117, Hongtai Bld., Songling rd, Zichuan,Zibo,Shandong,China
Shanghai Forever Synthesis Co.,Ltd.

Contact:021-61124658

Address:Zhoukang Road,Pudong New District,Shanghai,China
Jiangxi Hessence Chemicals Co., Ltd.

Contact:+86 796 3511924

Address:Chengxi Industrial Park, Jishui County, Jiangxi Province 331600 China.
Hangzhou Hysen Pharma co.,Ltd.

website:http://www.hysenpharma.cn/

Contact:0086-571-88298791

Address:#701,Gudun Road Hangzhou

Relevant to this article

Photoisomerization of stilbene dendrimers: The need for a volume-conserving isomerization mechanism

Doi:10.1562/0031-8655(2002)076<0596:POSDTN>2.0.CO;2
(2002)
Doi:10.1002/jps.2600531217
(1964)
Design, synthesis, and biological evaluation of novel non-piperazine analogues of 1-[2-(diphenylmethoxy)ethyl]- and 1-[2-[bis(4- fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazines as dopamine transporter inhibitors

Doi:10.1021/jm990161h
(1999)
REACTIONS OF BENZOYLISOTHIOCYANATE WITH ACETOACETANILIDE: SYNTHESIS OF PYRAZOLE, PYRIDINE, PYRIMIDINE, PYRAZOLO<3,4-d>PYRIMIDINE, PYRAZOLO<4,3-d>PYRIMIDINE AND PYRIDO<4,3-d>OXAZINE DERIVATIVES

Doi:10.1135/cccc19930947
(1993)
Synthesis of β-Methyl Alcohols: Influence of Alkyl Chain Length on Diastereoselectivity and New Attractants of Rhynchophorus ferrugineus

Doi:10.1021/acs.jafc.1c01875
(2021)
Annulation reaction of (triphenylmethyl)allene on a cationic metal complex and the reaction mechanism

Doi:10.1021/om00034a032
(1993)

Article Doi