14959-31-0 Usage
Description
N-(6-Chloro-3-pyridazinyl)acetamide is a chemical compound characterized by the molecular formula C7H7ClN2O. It is an acetamide derivative featuring a 6-chloro-3-pyridazinyl group, which endows it with a diverse range of potential applications, particularly in the pharmaceutical sector. This versatile compound is known for its potential biological activities, such as anticonvulsant and antitumor properties, making it a subject of ongoing research for its therapeutic uses.
Uses
Used in Pharmaceutical Industry:
N-(6-Chloro-3-pyridazinyl)acetamide is utilized as a key intermediate in the synthesis of various pharmaceutical agents and drugs. Its unique chemical structure allows it to be a building block for the development of new medications with potential therapeutic benefits.
Used in Medicinal Chemistry Research:
In the field of medicinal chemistry, N-(6-Chloro-3-pyridazinyl)acetamide is employed as a compound of interest for studying its anticonvulsant properties. This research aims to develop new treatments for epilepsy and other seizure disorders, where its potential to modulate neuronal activity could provide significant clinical advantages.
Used in Oncology Research:
N-(6-Chloro-3-pyridazinyl)acetamide is also used as a subject of antitumor research. Its potential to inhibit tumor growth and affect cancer cell metabolism makes it a promising candidate for the development of novel anticancer drugs, which could lead to more effective therapies for various types of cancer.
Used in Drug Design and Development:
N-(6-Chloro-3-pyridazinyl)acetamide's structural features make it a valuable asset in drug design and development. Researchers use N-(6-Chloro-3-pyridazinyl)acetamide to create new molecular entities that can target specific biological pathways or receptors, potentially leading to more selective and effective pharmaceuticals with fewer side effects.
Check Digit Verification of cas no
The CAS Registry Mumber 14959-31-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,4,9,5 and 9 respectively; the second part has 2 digits, 3 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 14959-31:
(7*1)+(6*4)+(5*9)+(4*5)+(3*9)+(2*3)+(1*1)=130
130 % 10 = 0
So 14959-31-0 is a valid CAS Registry Number.
InChI:InChI=1/C6H6ClN3O/c1-4(11)8-6-3-2-5(7)9-10-6/h2-3H,1H3,(H,8,10,11)
14959-31-0Relevant articles and documents
Amide anions as unexpected activating groups in nucleophilic heteroaromatic substitution
Gillies,Gillies, Iain,Rees,Rees, Charles W.
, p. 4065 - 4068 (1996)
Nucleophilic displacement of halide by alkoxide in pyridazines, phthalazines, a thiazole and a thiadiazole is unexpectedly activated by acetamido anion substituents compared to neutral amido and amino substituents.
THERAPEUTIC PYRIDAZINE COMPOUNDS AND USES THEREOF
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Page/Page column 142, (2016/09/26)
The present invention relates to compounds of formula (I): (I) and salts thereof, wherein: R1-R4 have any of the values defined in the specification, and compositions and uses thereof. The compounds are useful as inhibitors of BRG1, BRM and/or PB1. Also included are pharmaceutical compositions comprising a compound of formula (I) or a pharmaceutically acceptable salt thereof, and methods of using such compounds and salts in the treatment of various BRG1-mediated disorders, BRM-mediated disorders and/or PB1-mediated disorders.
Pyridazines. LI. Synthetic approaches to pyridazino(2,3-a)-1,3,5-triazines, a novel heterocyclic system.
Zupan,Stanovnik,Tisler
, p. 2960 - 2963 (2007/10/05)
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