149669-44-3 Usage
General Description
5-Methyl-3-piperidin-4-yl-1H-indole hydrochloride, also known as 3-(piperidin-4-yl)-5-methyl-1H-indole hydrochloride, is a chemical compound with potential biological and pharmacological activities. It belongs to the class of indole alkaloids and is structurally related to serotonin and other neurotransmitters. It has been studied for its potential role in modulating the central nervous system and for its potential therapeutic applications in the treatment of various neurological and neuropsychiatric disorders. It is also being investigated for its potential use in drug development and medicinal chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 149669-44-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,9,6,6 and 9 respectively; the second part has 2 digits, 4 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 149669-44:
(8*1)+(7*4)+(6*9)+(5*6)+(4*6)+(3*9)+(2*4)+(1*4)=183
183 % 10 = 3
So 149669-44-3 is a valid CAS Registry Number.
InChI:InChI=1/C14H18N2.ClH/c1-10-2-3-14-12(8-10)13(9-16-14)11-4-6-15-7-5-11;/h2-3,8-9,11,15-16H,4-7H2,1H3;1H
149669-44-3Relevant articles and documents
Pyrazole-based cathepsin S inhibitors with improved cellular potency
Wei, Jianmei,Pio, Barbara A.,Cai, Hui,Meduna, Steven P.,Sun, Siquan,Gu, Yin,Jiang, Wen,Thurmond, Robin L.,Karlsson, Lars,Edwards, James P.
, p. 5525 - 5528 (2007)
High potency pyrazole-based noncovalent inhibitors of human cathepsin S (CatS) were developed by modification of the benzo-fused 5-membered ring heterocycles found in earlier series of CatS inhibitors. Although substitutions on this heterocyclic framework