149692-82-0

Basic information

• Product Name: 3-PIPERIDIN-4-YL-1H-PYRROLO[2,3-6]PYRIDINE HCL
• Synonyms: 3-PIPERIDIN-4-YL-1H-PYRROLO[2,3-6]PYRIDINE HCL;1H-Pyrrolo[2,3-b]pyridine, 3-(4-piperidinyl)-;3-Piperidin-4-yl-1H-pyrrolo[2,3-6]pyridine hydrochloride
• CAS NO: 149692-82-0
• Molecular Formula: C₁₂H₁₅N₃
• Molecular Weight: 237.73
• Mol File: 149692-82-0.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 401.6°C at 760 mmHg
• Flash Point: 196.7°C
• Appearance: /
• Density: 1.167g/cm³
• Vapor Pressure: 1.17E-06mmHg at 25°C
• Refractive Index: 1.628
• PKA: 10.29±0.10(Predicted)
• CAS DataBase Reference: 3-PIPERIDIN-4-YL-1H-PYRROLO[2,3-6]PYRIDINE HCL(CAS DataBase Reference)
• NIST Chemistry Reference: 3-PIPERIDIN-4-YL-1H-PYRROLO[2,3-6]PYRIDINE HCL(149692-82-0)
• EPA Substance Registry System: 3-PIPERIDIN-4-YL-1H-PYRROLO[2,3-6]PYRIDINE HCL(149692-82-0)

Safety Data

• Hazardous Substances Data: 149692-82-0(Hazardous Substances Data)

Usage

General Description

3-PIPERIDIN-4-YL-1H-PYRROLO[2,3-6]PYRIDINE HCL is a chemical compound that is commonly used in pharmaceutical research and development. It is a pyrrolopyridine derivative that contains a piperidine ring and is often used as a building block for the synthesis of various pharmaceutical compounds. The hydrochloride (HCL) salt form of this compound is often used for its improved solubility and stability in aqueous solutions. This chemical is known for its potential in the treatment of various diseases, including cancer and neurological disorders, and it continues to be studied for its pharmacological properties and potential therapeutic applications.

InChI:InChI=1/C12H15N3/c1-2-10-11(8-15-12(10)14-5-1)9-3-6-13-7-4-9/h1-2,5,8-9,13H,3-4,6-7H2,(H,14,15)

Upstream product

• 281658-42-2 3-(1,2,3,6-tetrahydro-pyridin-4-yl)-1H-pyrrolo[2,3-b]pyridine 

Downstream Products

• 612097-74-2 4-(1H-pyrrolo[2,3-b]pyridin-3-yl)-piperidine-1-carboxylic acid ethyl ester 

Relevant articles and documents

3-PIPERIDIN-4-YL-INDOLE ORL-1 RECEPTOR MODULATORS

The present invention is directed to novel 3-piperidin-4-yl-indole derivatives of formula (I) and forms thereof, wherein X, R1, R2, R3, R4 and R5 are as herein defined, pharmaceutical compositions thereof and use as ORL-1 receptor modulators for treating, preventing or ameliorating ORL-1 receptor mediated disorders and conditions.

3-SUBSTITUTED 3,4-DIHYDRO-THIENO[2,3-D]PYRIMIDINE-4-ONE-DERIVATIVES, PRODUCTION AND USE THEREOF

The invention relates to 3,4-dihydro-thieno[2,3-d]pyrimidinde-4-one-derivatives which are substituted at 3-position with 5-membered heteroaryl which can be condensed with an aryl or heteroaryl radical. The heteroaryl and, optionally, the condensed aryl or heteroaryl radical 1,2 or 3 can independently include selected substitutents from C1-5-alkyl, C1-5-alkoxy, C1-5-alkylthio, halogen, CN, halogen-C1-5-alkyl, halogen-C1-5alkoxy, hydroxy, -NH2, -N(R6)2, -NH(R6), aryl, aryloxy, aralkyl, aralkyloxy and heteroaryl, the substituents aryl, aryloxy, aralkyl, aralkyloxy and heteroaryl 1,2 or 3 independently include selected substituents from C1-5-alkythio, halogen, CN, halogen-C1-5-alkyl, halogen-C1-5alkoxy, hydroxy, -NH2, -N(R6)2 and -NH(R6). The invention also relates to the production and use of said derivatives, especially for therapeutical purposes, e.g. in the treatment of depression.