612097-74-2 Usage
Structure
Ethyl ester derivative of 4-(1H-pyrrolo[2,3-b]pyridin-3-yl)-1-piperidinecarboxylic acid
Receptor interaction
Potent and selective antagonist of the adenosine A1 receptor
Therapeutic applications
Potential use in the treatment of various diseases and disorders, including cardiovascular and neurodegenerative conditions
Analgesic and anxiolytic properties
Has shown promise as an analgesic and anxiolytic agent
Research and development
Further studies may lead to the discovery of new pharmaceutical drugs with improved efficacy and safety profiles
Check Digit Verification of cas no
The CAS Registry Mumber 612097-74-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,1,2,0,9 and 7 respectively; the second part has 2 digits, 7 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 612097-74:
(8*6)+(7*1)+(6*2)+(5*0)+(4*9)+(3*7)+(2*7)+(1*4)=142
142 % 10 = 2
So 612097-74-2 is a valid CAS Registry Number.
InChI:InChI=1/C15H19N3O2/c1-2-20-15(19)18-8-5-11(6-9-18)13-10-17-14-12(13)4-3-7-16-14/h3-4,7,10-11H,2,5-6,8-9H2,1H3,(H,16,17)
612097-74-2Relevant articles and documents
Synthesis and structure-activity relationships of piperidinylpyrrolopyridine derivatives as potent and selective H1 antagonists
Fonquerna, Silvia,Miralpeix, Montse,Pages, Lluis,Puig, Carles,Cardus, Arantxa,Anton, Francisca,Vilella, Dolors,Aparici, Monica,Prieto, Jose,Warrellow, Graham,Beleta, Jorge,Ryder, Hamish
, p. 1165 - 1167 (2005)
The synthesis and structure-activity relationships of piperidinylpyrrolopyridines as potent and selective H1 antagonists are discussed. It was found that the nature of the acid chain bonded to piperidine was a key feature for maintaining both the duration of action in vivo and lack of sedative properties.
