1497410-63-5Relevant academic research and scientific papers
Organocatalytic mannich reactions on a carbapenem core - Synthesis of mannich bases and bicyclic diazanonanes
Cele, Zamani E. D.,Pawar, Sachin A.,Naicker, Tricia,Maguire, Glenn E. M.,Arvidsson, Per I.,Kruger, Hendrik G.,Govender, Thavendran
, p. 2253 - 2260 (2014)
An efficient diastereoselective synthesis of carbapenem Mannich bases was developed using organocatalysis. This method also provides a route to new highly functionalized diazabicyclo[4.2.1]nonanes of proposed biological significance.
Organocatalyzed stereospecific C-C bond formation of β-lactams
Pawar, Sachin A.,Alapour, Saba,Khanyase, Sibusiso,Cele, Zamani E. D.,Chitti, Srinivas,Kruger, Hendrik G.,Govender, Thavendran,Arvidsson, Per I.
supporting information, p. 8294 - 8297 (2013/12/04)
Herein, we report the development of mild, organocatalyzed routes to novel carbapenam derivatives through aldol, Mannich and Michael C-C bond forming reactions.
