149764-53-4Relevant articles and documents
Synthesis of 1,4-Dicarbonyl Compounds from Silyl Enol Ethers and Bromocarbonyls, Catalyzed by an Organic Dye under Visible-Light Irradiation with Perfect Selectivity for the Halide Moiety over the Carbonyl Group
Esumi, Naoto,Suzuki, Kensuke,Nishimoto, Yoshihiro,Yasuda, Makoto
supporting information, p. 5704 - 5707 (2016/11/17)
We report the visible-light-induced radical coupling reaction of silyl enol ethers with α-bromocarbonyl compounds to give 1,4-dicarbonyls. The reaction was effectively accelerated using an inexpensive organic dye (eosin Y) as a photoredox catalyst. 1,4-Dicarbonyl compounds alone were afforded, without the generation of carbonyl adducts of the α-halocarbonyls, which are usually generated in the presence of fluoride anions or Lewis acids. A variety of silyl enol ethers, α-bromoketones, α-bromoesters, and α-bromoamides were applied to this system to produce the coupling compounds.
SYNTHESIS OF 1,4-DIKETONES, 3,4-EPOXY KETONES, AND 2,4-DISUBSTITUTED FURANS BASED ON THE PRODUCTS FROM CONDENSATION OF THE MAGNESIUM ENOLATES OF KETONES WITH α-BROMO KETONES
Kel'in, A. V.,Kulinkovich, O. G.
, p. 202 - 206 (2007/10/02)
4-Bromo-3-hydroxy ketones were obtained by the condensation of methyl ketones with 2-bromo ketones in the presence of tert-butoxymagnesium bromide or by the action of organomagnesium compounds on 2-bromo ketones.The reaction of 4-bromo-3-hydroxy ketones w
