149771-23-3Relevant academic research and scientific papers
cGAS ANTAGONIST COMPOUNDS
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Paragraph 0246, (2017/11/06)
Disclosed are novel compounds of Formula (I) that are cGAS antagonists, methods of preparation of the compounds, pharmaceutical compositions comprising the compounds, and their use in medical therapy.
PYRIMIDINE DERIVATIVES AS CANNABINOID RECEPTOR MODULATORS
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Page/Page column 30, (2010/02/13)
The present invention relates to novel pyrimidine derivatives such as compounds of the formula (I) and the use of such compounds or pharmaceutical compositions thereof in the treatment of diseases, particularly pain, which are mediated by the activity of the cannabinoid 2 receptor.
Synthesis, antiviral (HSV-1) and antimycotic activities of ethyl or methyl 2,4-disubstituted 5-pyrimidinecarboxylates, 2,4-disubstituted 5-pyrimidinecarboxylic acids and 2,4-disubstituted pyrimidines
Sansebastiano,Mosti,Menozzi,Schenone,Muratore,Petta,Debbia,Pesce Schito,Schito
, p. 335 - 355 (2007/10/02)
The synthesis of ethyl or methyl 4-substituted or unsubstituted 2-methylthio-5-pyrimidinecarboxylates 3 a-i and 8 o mainly by reaction of ethyl or methyl 2-dimethylaminomethylene-3-oxoalkanoates with 2-methylisothiourea is described. Also some ethyl 2-sub
