149798-26-5

Upstream product

• 149798-23-2 5-(6-N-(trifluoroacetyl)-aminohexyl)-2'-deoxyuridine 
• 40615-36-9 4,4'-dimethoxytrityl chloride 
• 149798-19-6 3',5'-di-O-trifluoroacetyl-5-iodo-2'-deoxyuridine 
• 149798-23-2 5-(6-N-(trifluoroacetyl)aminohexyl)-2'-deoxyuridine 
• 149798-20-9 5-(6-N-(trifluoroacetyl)amino-1-hexynyl)-2'-deoxyuridine 
• 54-42-2 5-Iodo-2'-deoxyuridine 

Relevant academic research and scientific papers

Antisense oligonucleotides comprising 5-aminoalkyl pyrimidine nucleotides

Replacement of the natural nucleotides with unnatural zwitterionic nucleotides having a cationic moiety tethered to the base (or analog thereof) results in oligodeoxynucleotides with diminished charge but undiminished ability to complex with DNA at low io

Zwitterionic DNA

As a strategy to make DNA net charge neutral, oligodeoxynucleotides bearing pyrimidine 5-ω-aminohexyl substituents have been synthesized and characterized. The resultant zwitterionic oligomers bind to natural DNA at low ionic strength as well or better th