149913-92-8

Basic information

• Product Name: 6-benzyloxy-2-phenyl-1H-indole
• Synonyms: 6-benzyloxy-2-phenyl-1H-indole
• CAS NO: 149913-92-8
• Molecular Weight: 299.372
• Mol File: 149913-92-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 6-benzyloxy-2-phenyl-1H-indole(CAS DataBase Reference)
• NIST Chemistry Reference: 6-benzyloxy-2-phenyl-1H-indole(149913-92-8)
• EPA Substance Registry System: 6-benzyloxy-2-phenyl-1H-indole(149913-92-8)

Safety Data

• Hazardous Substances Data: 149913-92-8(Hazardous Substances Data)

Upstream product

• 886853-78-7 5-benzyloxy-2-(2,2-dibromo-vinyl)-phenylamine 
• 98-80-6 phenylboronic acid 
• 149913-89-3 allyl α-phenyl-2-amino-4-benzyloxyphenethyl carbonate 
• 149913-83-7 α-phenyl-2-amino-4-benzyloxyphenethyl alcohol 
• 149913-79-1 α-phenyl-4-benzyloxy-2-nitrophenethyl alcohol 
• 100-52-7 benzaldehyde 
• 24239-67-6 4-(benzyloxy)-1-methyl-2-nitrobenzene 

Relevant articles and documents

A highly selective tandem cross-coupling of gem-dihaloolefins for a modular, efficient synthesis of highly functionalized indoles

(Chemical Equation Presented) A highly efficient method of indole synthesis using gem-dihalovinylaniline substrates and an organoboron reagent was developed via a Pd-catalyzed tandem intramolecular amination and an intermolecular Suzuki coupling. Aryl, alkenyl, and alkyl boron reagents are all successfully employed, making for a versatile modular approach. The reaction tolerates a variety of substitution patterns on the aniline leading to indoles with group at C2-C7. The orthogonal approach of the sequential copper- and palladium-mediated synthesis of 1,2-diarylindoles exploited the wide availability of diverse organoboron reagents.

Palladium- or ruthenium-catalyzed synthesis of 2-phenylindoles

-