149914-82-9

Usage

Type of compound

Ketone derivative

Structure

Benzene ring substituted with a chlorine and fluorine atom

Industry use

Pharmaceutical industry

Applications

Synthesis of various pharmaceutical products, production of drugs, agrochemicals, and other fine chemicals

Role

Versatile building block for the synthesis of various organic molecules

Safety precautions

Corrosive and harmful if not used properly, handle with care

Upstream product

• 925-90-6 ethylmagnesium bromide 
• 60702-69-4 2-chloro-4-fluorobenzonitrile 
• 84194-36-5 2-chloro-4-fluorobenzaldehyde 

Relevant academic research and scientific papers

INDOLO-SUBSTITUTED-PIPERIDINE COMPOUNDS AS ESTROGEN RECEPTOR DEGRADING AGENT

Disclosed is a new indole compound, in particular, the compound as shown in formula (I), and a preparation method, pharmaceutical composition and use thereof as an estrogen receptor down-regulator in preparing drugs for treating estrogen receptor-positive breast cancer.

3-aryluracil derivatives and their use for weed control

3-Aryluracil derivatives of the formula I STR1 in which --W-- is the group STR2 where the ring nitrogen atom is bonded via the C atom; R1 is hydrogen, C1 -C4 alkyl, C1 -C4 haloalkyl, C3 alkenyl or C4 alkenyl or C3 alkynyl or C4 alkynyl; R2 is halogen or cyano; R3 is hydrogen or halogen; R4 is hydrogen, halogen or C1 -C4 alkyl; R5 is C1 -C4 alkyl or C1 -C4 haloalkyl; or R4 and R5 together are --(CH2)n --; n is the number 3 or 4; R13 is C1 -C4 alkyl, C3 alkenyl or C4 alkynyl or C3 alkynyl or C4 alkynyl; and Q is one of the groups a) to e): STR3 where R6 to R12 are substituents, m is 3, 4 or 5, X is oxygen or sulfur and t is 2, 3 or 4, and if R1 is hydrogen, the agrochemically acceptable salts of compounds of the formula I. the compounds of formula I have herbicidal properties and are suitable as the active ingredient in a herbicide.