150015-89-7

Upstream product

• 4224-96-8 3-phenyl-1-p-tolylprop-2-en-1-one 
• 105-53-3 diethyl malonate 
• 996-82-7 sodium diethylmalonate 
• 14802-30-3 (E)-1-(4-methylphenyl)-3-phenyl-2-propen-1-one 

Downstream Products

• 77565-58-3 5-oxo-3-phenyl-5-p-tolyl-valeric acid 
• 876482-37-0 (3-oxo-1-phenyl-3-p-tolyl-propyl)-malonic acid 
• 14802-30-3 (E)-1-(4-methylphenyl)-3-phenyl-2-propen-1-one 
• 105-53-3 diethyl malonate 
• 1345614-36-9 diethyl 2-hydroxy-2-(3-(4-methylphenyl)-3-oxo-1-phenylpropyl)malonate 
• 1274820-56-2 2-(4-methyl phenyl)-4-phenyl-2-cyclopenten-1-one 
• 77565-70-9 5-Oxo-3-phenyl-5-p-tolyl-pentanoic acid methyl ester 

Relevant academic research and scientific papers

Mg-promoted facile and selective intramolecular cyclization of aromatic δ-ketoesters

Treatment of various types of aromatic δ-ketoesters 2, 7, and 9 with Mg-turnings for Grignard reaction at -5 to 0 °C in N,N-dimethylformamide (DMF) containing trimethylsilyl chloride (TMSCl) brought about selective and reductive intramolecular cyclization

Synthesis and Stereochemistry of cis- and trans- 4,6-Diaryl-2-piperidones

Two-carbon 1,4-addition to variously substituted chalcones (3) and subsequent two-step reductive amination, and cyclisation via oxime intermediates resulsts in cis- (1) and trans- (2) 4,6-diarylpiperidones in high yields.The configuration and conformation